Commissariat a L'energie Atomique

Commissariat &#xc0; L'&#xc9;nergie Atomique Et Aux &#xc9;nergies Alternatives

Biomerieux, Inc.

Institut National De La Sante Et De La Recherche Medicale

Pascale Pham

Laurent Drazek

Jean-luc Achard

Frederic Ginot

Adrien Plecis

Cyril Condemine

Stéphane Bonnet

François Perraut

Jean-Francois Beche

Florent Dupont

Olivier David

Alexandre Fouchard

Stephane Bonnett

Jean-François Beche

An EIT or differential EIT method in which measurements of voltage differences between electrodes are performed according to a measurement configuration in which at least one of the electrodes injecting a current in the medium being investigated is also used for performing a measurement of the voltage difference. The contact impedances of the different electrodes are measured thanks to a counter-electrode having a contact area with the medium much higher than the contact area of a unit electrode. The measurement of a contact impedance is performed by impedance spectroscopy by comparison with the impedance spectrum of an equivalent circuit. The contact impedances allow voltage drops in the injection electrodes to be calculated the voltage differences between these electrodes and to be corrected. Alternatively, the contact impedances can be used to correct or complete the direct model.

Method for imaging a medium through electrical measurements with a contact impedance correction

An electrical stimulation system including: a mechanism generating at least one electrical signal to be applied to a biological tissue that is to stimulated and measuring a response of the biological tissue to each electrical signal; a calculation mechanism estimating, based on each electrical signal and on a corresponding response of the biological tissue, at least one parameter of an electrical model of the biological tissue and its interface with the electrical stimulation system and determining, using the model, at least one parameter of a stimulation pulse to be applied to the biological tissue by the electrical stimulation system; and a mechanism generating a stimulation pulse to be applied to the biological tissue.

Devices for electrical stimulation of a biological tissue and method for calibrating same

A device for dielectrophoretic separation of particles contained in a fluid, includes two sets of electrodes, each of the two sets of electrodes being brought to a different potential, so as to generate an electric field inside said fluid. The two sets of electrodes are positioned inside a chamber, itself provided with a particle collecting surface. Each of the two sets of electrodes is immersed in the fluid inside the chamber and is located in a plane different from the plane of the particle collecting surface. The two sets of electrodes are supplied with electrical current in phase opposition. The potential of each of the two sets of electrodes have a gradient based on the distance along a direction perpendicular to the plane of the particle collecting surface.

Device for dielectrophoretic separation of particles contained in a fluid

The invention concerns a device for isolating, on a reactive surface, an analyte from a liquid sample containing the analyte.

Method and device for isolating and/or determining an analyte

The invention concerns a method for isolating an analyte from an initial sample containing same, on a reactive surface in contact with all or part of the initial sample, characterized in that it comprises the following steps which consist in: 1) forming and/or maintaining a reaction volume entity, comprising an internal liquid medium, corresponding to all or part of the initial sample, the entity including an interface with an external medium, having with the latter a surface tension; 2) applying a temperature difference between at least two thermal points located: a) proximate to and/or b) on the surface and/or c) within said entity, said thermal points being respectively different, in terms of temperature and positioning; 3) fixing the analyte on the reactive surface, positioned on the path of forces convection generated by the temperature difference.

Method and device for isolation and/or determination of an analyte

Growing community of inventors

Crolles, France

Pascale Pham