Boehringer Ingelheim International Gmbh

Pascale A J Pouzet

Peter Nickolaus

Soojin Kim

Xudong Wei

Rogelio Perez Frutos

Ulrike Werthmann

Bing-Shiou Yang

Nitinchandra D Patel

Thomas Gabriel Tampone

Jason Alan Mulder

Chris Hugh Senanayake

Chris Hugh Sananayake

Piperidino-dihydrothienopyrimidine sulfoxides of formula I wherein:

Piperidino-dihydrothienopyrimidine sulfoxides and their use for treating COPD and asthma

The invention relates to novel piperidino-dihydrothienopyrimidine sulfoxides of formula I, wherein Ring A is a 6-membered aromatic ring which may optionally comprise one or two nitrogen atoms andwherein R is Cl andwherein R may be located either in the para-, meta- or ortho-position of Ring A,wherein S* is a sulphur atom that represents a chiral center,and all pharmaceutically acceptable salts, enantiomers and racemates, hydrates and solvates thereof and the use of these compounds for the treatment of inflammatory or allergic diseases of the respiratory tract such as COPD or asthma.

The invention relates to novel piperidino-dihydrothienopyrimidine sulfoxides of formula I, 

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Biberach an der Riss, Germany

Pascale A J Pouzet