Université De Bretagne Occidentale

Centre National De La Recherche Scientifique

Institut National De La Sante Et De La Recherche Medicale

Centre Hospitalier Universitaire De Brest

Ecole Nationale Superieure De Chime De Rennes

Pascal Delepine

Claude Ferec

Tristan Montier

Thierry Benvegnu

Daniel Plusquellec

Pierre Lehn

Jean-Claude Clement

Jean-Jacques Yaouanc

Hervé Des Abbayes

Gildas Rethore

Mickaelle Scahet

Karine Le Ny

Mickaelle Sachet

The invention relates to a compound of general formula (I): where X=0 or 1, Z=O, S or CH, Rand Rindependently=OH or OY, where Y=a protecting group, OR, where R=a monosaccharide or disaccharide group, A-CH&#x2014;N(CH), X', where X=halogen, A=an amide (NHC(O)) or ester (OC(C)) bond, OPO(OM), where M=an alkyli or alkyli earth metal, OP(O)O&#x2014;O(CH)&#x2014;N(CH), A-(PEG-A)-R, where n=0 or 1, PEG=a polyethyleneglycol of molecular weight X, where Xbeing less than or equal to 5,000 daltons, Aand Aindependently=a ether (O), ester (OC(O)), amide (NHC(O)), urea (NHC(O)NH), thiourea (NHC(S)NH), or thioether (S) bond R=a directing agent. 

Analogue compounds of archaebacterial membrane lipids and liposomal compounds integrating such compounds

The present invention has for an object a cationic lipophilic compound of the following general formula (I): wherein:

Lipophilic compounds and uses thereof

Growing community of inventors

Bohard, France

Pascal Delepine