Corium International, Inc.

Corium Corporation

A.v. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences

Corium Pharma Solutions, Inc.

A.v. Topchiey Institute of Petrochemical Synthesis, Russian Academy of Sciences

Panther Life Sciences Corporation

A.v. Topchiev Institute of Petrochemical Synthesis

Parminder Singh

Eun Soo Lee

Gary Wynn Cleary

Amit K Jain

Mikhail M Feldstein

Robert Wade Worsham

Danir F Bayramov

Guohua Chen

Sri Mudumba

Joseph Creagan Trautman

Valery G Kulichikhin

Anthony Le

Steven Richard Klemm

Ashutosh Shastry

Adrian Faasse

Zhongli Ding

Danny Lee Bowers

Doug Bourne

Esi Ghartey-Tagoe

Danir F Bairamov

Danir R Bairamov

Douglas Joseph Scott Bourne

Nicolai A Platé

Danir Bairamov

Mikhail Borisovich Novikov

Andy Klemm

Janet Wendorf

Appala Sagi

Steve Williams

Andrew Richard Klemm

Anatoly E Chalykh

Nicolai A Platè

Adrian L Faasse

Sergey Antonov

Danir Bayamov

Danir Bayramov

Mikhail B Novikov

Nicolai Plate

Steven Richard Kelmm

Andy Kelmm

A method and a drug delivery system for transdermally administering parathyroid hormone (PTH) in a pulsatile fashion are provided, where the drug delivery system comprises an array of microprojections each comprising PTH.

Method and device for transdermal delivery of parathyroid hormone using a microprojection array

Devices, systems, compositions and methods for long term or prolonged transdermal administration of an active agent are provided.

Systems comprising a composite backing and methods for long term transdermal administration

Systems and methods for long term transdermal administration

An applicator for a microprojection array is described. In one embodiment, the applicator comprises an energy-storing element. Application of force causes the compressed energy-storing element to extend or transition from first and second configurations, releasing stored energy to deploy a holding member in the application which is configured to hold an array of microprojections. In another embodiment, the applicator comprises an energy storing element with two stable configurations, a first stable configuration and second stable configuration. Application of force causes the energy-storing element to transition from the higher energy first stable configuration to the lower energy second stable configuration, releasing the difference in energies of the two states to deploy a holding member in the application which is configured to hold an array of microprojections.

Applicators for microneedles

Microstructure arrays and methods for using and manufacturing the arrays are described.

Microarray for delivery of therapeutic agent and methods of use

An adhesive matrix and adhesive formulation are described. The adhesive matrix is comprised of a hydrophilic domain and a hydrophobic domain, and a therapeutically active agent contained in the matrix in a supersaturated, stable, condition. The hydrophilic domain and the hydrophobic domain are co-soluble in a solvent system, to provide a homogeneous blend in which the active agent is solubilized. The proportion of the hydrophilic domain and hydrophobic domain is selected to optimize, or maximize, solubility of active agent in the matrix.

Adhesive matrix with hydrophilic and hydrophobic domains and a therapeutic agent

Methods, compositions, and devices for transdermally administering an active agent such as memantine are provided.

Transdermal adhesive composition comprising a volatile liquid therapeutic agent having low melting point

Applicators for a microprojection array and methods of using the applicators are described.

Microprojection applicators and methods of use

A transdermal delivery system for systemic delivery of donepezil is described, where the system comprises an adhesive matrix drug reservoir layer comprised of a copolymer of acrylic acid/vinyl acetate, triethyl citrate, and donepezil base generated in situ by reaction of donepezil HCl and an alkaline salt. The system is provided for treatment of Alzheimer's disease, and achieves transdermal delivery of the therapeutic agent at steady state that is bioequivalent to administration of the therapeutic agent orally.

Methods for treating alzheimer's disease with donepezil transdermal system

Devices and methods for using and manufacturing microstructure arrays having at least a detachable distal area are described.

Growing community of inventors

Union City, CA, United States of America

Parminder Singh