The United States of America, as Represented by the Secretary, Department of Health and Human Services

Northwestern University

Parmede Vakil

Timothy J Carroll

Sumeeth Jonathan

Michael Hurley

Rajiv Menon

Renee Qian

Yong Jeong

Sameer Ansari

A system for perfusion and diffusion MR imaging of a portion of patient anatomy includes an RF (Radio Frequency) signal generator for generating RF excitation pulses in anatomy and enabling subsequent acquisition of associated RF echo data. A magnetic field gradient generator generates anatomical volume select magnetic field gradients for phase encoding and readout RF data acquisition in a three dimensional (3D) anatomical volume. The RF signal generator and the gradient generator acquire within a single MR imaging scan, perfusion image data of the 3D volume, at least partially in the presence of contrast agent, and diffusion image data of the 3D volume.

System and method for perfusion and diffusion MR imaging

In one aspect of the disclosure, an MRI-based system includes an MRI scanner having a first axis and a first plane perpendicular to the first axis, a pulse sequence module configured to provide a 3D pulse sequence to the MRI scanner, and a control module configured to instruct the MRI scanner to conduct radial k-space samples having N second planes that each are perpendicular to the first plane and through which the first axis passes, N being an integer greater than 1. The 3D pulse sequence instructs the MRI scanner to a radio-frequency (RF) pulse, conduct a gradient readout in the first plane, and conduct a gradient readout in one of the N second planes.

Imaging-based diagnostic apparatus and methods for quantifying cerebral vascular reserve

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Chicago, IL, United States of America

Parmede Vakil