Ausimont S.p.a.

Neuroscienze Pharmaness S.c.a.r.l.

Solvay Solexis S.p.a.

Kemotech S.r.l.

Kemtech S.r.l.

Neuroscienze Pharmaness S.c.a.r.i.

Paolo Lazzari

Stefania Ruiu

Gerard Aime Pinna

Gabriele Murineddu

Alba Chittofrati

Daria Lenti

Luca Pani

Julio A Abusleme

Matteo Zanda

Monica Sani

Giovanni Loriga

Vincenzo Arcella

Giulio Brinati

Ilaria Manca

Paolo Fadda

Luca Caluso

Giovanni Lorgia

Pharmaceutical compounds

Diazapolycyclic compounds having affinity for the opioidergic receptors, preferably for the delta opioidergic receptors, with central and/or peripheral activity, having formula:A-D-T&#x2003;&#x2003;(I)wherein: 

Substituted 3,8-diazabicyclo[3.2.1]octane compounds

Tubulysine compounds of formula (A) having a high cytotoxicity wherein:B is selected from CH, CH&#x2014;CHor CH&#x2014;CH&#x2014;CH,D is an aromatic linker,Xis alkyl or alkenyl,Xis selected from the X, substituted or non substituted, selected from: aryl, heteroaryl, arylalkyl, cycloalkylalkyl, heterocycloalkylalkyl, or heteroarylalkyl,X: alkylene-O-alkyl, wherein alkylene is C-C,X: CH&#x2014;O-alkyl,Xis selected from H, or together with Xforms the group &#x2550;O,Xis selected from H, halogen, OH, SH, alkyl, alkenyl, (OR)&#x2014;OR, OC(O)R, NRR, or together with Xforms the group &#x2550;O,Ris an alkylene,n is zero or an integer from 1 to 10,Rand R, equal to or different from each other, have the following meanings:

Tubulysin compounds with high cytotoxicity, pharmaceutical compositions thereof, and method of use thereof

Nonane and decane diazabicyclic derivatives having homopiperazine as main ring, having affinity for the opioidergic &#x3bc; and/or &#x3b4; and/or k receptors and/or for all their receptorial subclasses, with central and/or peripheral activity, having formula (I), the isomeric forms and their mixtures included, wherein one or more atoms are in the corresponding isotopic forms: 

Liquid-based phamaceutical and/or veterinary and/or nutraceutical compositions comprising non pathogenic sporogenic bacteria, component SP), and the following components:

Compositions of spores of non pathogenic bacteria

Pyrazole derivatives of the following formula (I), having affinity for the cannabinoidergic CB1 and/or CB2 receptors: wherein:

Tricyclic pyrazole derivatives of the following formula (I) having affinity for the cannabinoidergic CB1 and/or CB2 receptors: wherein:

VDF polymerization process, optionally modified with small amounts of one or more fluoro-containing comonomers, carried out in the presence of a microemulsion comprising a (per) fluoropolyether having neutral end groups, having number average molecular weight between 400 and 3000, and a surfactant based on perfluoropolyethers with salified acid end groups, said surfactant having a number molecular weight Mn comprised between 400&#x2013;600 and having a distribution of molecular weights such that fractions having a number average molecular weight higher than 700 are not present, or are in amount less than 5% by weight.

VDF polymerization process

Polymerization process in suspension

Dispersions, obtained starting from a system formed by a (per)fluorinated polymer in polar solvent, comprising at least:

Fluoropolymer dispersions

Fluorinated greases comprising (by weight):

Fluorinated greases

Perfluoropolymer dispersions

Use of surfactants in the suspension polymerization of fluorinated monomers for preparing fluoropolymers containing hydrogen, said surfacants having the general formula:

Growing community of inventors

Cagliari, Italy

Paolo Lazzari