Chiesi Farmaceutici S.p.a.

Chinoin Pharmaceutical and Chemical Works Private Company Ltd.

Chiesi Farmaceutical S.p.a.

Chiesi Farmaceuticals S.p.a.

Paolo Chiesi

Paolo Ventura

Vittorino Servadio

Roberta Razzetti

Maurizio Del Canale

Stefano Bongrani

Gabriele Amari

Gaetano Brambilla

Renato De Fanti

Rossella Musa

Maurizio Civelli

Luciana Pavesi

Daniela Acerbi

Alberto Umile

Maurizio Delcanale

Raffaella Garzia

Marco Del Corno

Chiara Malvolti

Roberto Bilzi

Josef Szejtli

Maria Vikmon

Isabella Panza

Massimo Pasini

Rosa Mezzadri

Egbert Herting

Roberto Pighi

Wolfgang Gopel

Claudio Pietra

Elisabetta Armani

Fausto Pivetti

Fabio Carli

Eleonora Ghidini

Gino Villetti

Flavio Villani

Eva Fenyvesi

Bluetta Salsi

Roberta Rassetti

Massimo Giossi

Mario Varesco

Maurizio Redenti

Walter Recchia

Enrico Redenti

Eva Bernini

Luigi Tagliapietra

Ross De Salvo

Ivano Rondelli

Gianluigi Poli

The present invention concerns a method for treating a respiratory distress in a infant in need of such treatment, the method comprising intratracheal administration of a pulmonary surfactant by a thin tube. The invention also concerns a kit for performing said method.

Method of administration of a pulmonary surfactant

Administration of a modified natural surfactant in combination with a corticosteroid is effective for the prevention of bronchopulmonary dysplasia (BPD) and lowers the markers of pulmonary oxidative stress.

Therapeutic combination comprising a pulmonary surfactant and a steroid

The invention relates to carrier particles for use in pharmaceutical compositions for the pulmonary administration of medicaments by means of dry powder inhalers. In particular, the invention relates to a novel technological process for obtaining a carrier modified so as to improve the efficiency of redispersion of active particles and hence increase the respirable fraction. After the treatment of the invention, the surface of said modified carrier particles can also be coated with a suitable additive so as to further improve the respirable fraction.

Modified carrier particles for use in dry powder inhalers

The present invention relates to optimized formulations of antiinflammatory steroids for nebulisation and a process for the preparation thereof. More particularly, the invention relates to formulations for monodose or multidose vials in the form of preservative-free stable solutions of a more acceptable osmolarity, which can effectively be nebulised with the nebulisers currently available on the market and are well-tolerated by patients.

Formulations of steroid solutions for inhalatory administration

The use of racemic or optically active compounds represented by formula (I) and the salts thereof wherein R is H or CHfor the preparation of pharmaceutical compositions for the therapy of ophthalmic disorders.

2-Aminotetralin derivatives for the therapy of glaucoma

A pharmaceutical formulation in the form of a fast dissolving tablet comprising an active ingredient, sodium glycine carbonate and an acid capable of reacting rapidly with sodium glycine carbonate to release carbon dioxide.

Pharmaceutical compositions containing an effervescent acid-base couple

The invention relates to a method of treatment of left ventricular dysfunction, by administering to a subject suffering from left ventricular remodeling a therapeutically effective amount of 5,6-dihydroxy-2-methylaminotetralin or 5,6-diisobutyroyl-oxy-2-methyl-aminotetralin, or a pharmaceutically acceptable salt thereof.

Aminotetralin derivatives for the therapy of cardiovascular diseases

Powdery pharmaceutical compositions including an active ingredient and carrier particles containing only a small amount of lubricant, 0.1-0.5% by weight, are used to prepare dry powder inhalers in order to increase the fine particle dose. A process for coating the surface of the carrier particles with such little amount of lubricant is also provided. Use of limited amount of lubricant is safe and provides ordered stable mixtures without segregation of the active particles during handling and before use.

Carrier mixed with additives having lubricant properties for preparing powdery pharmaceutical compositions for inhalation

The invention is directed to a process for the preparation of suspensions of drug particles for inhalation delivery, said process providing particles of optimized particle size and distribution homogeneously dispersed in the carrier. The process, which is also suitable for the preparation of sterile suspensions, includes the step of homogenizing and micronizing the formulation in a turboemulsifier provided with a high-potency turbine, optionally followed by a treatment in a high-pressure homogenizer. A further aspect of the invention is directed to a process for preparing micronized sterile beclomethasone dipropionate by gamma-irradiation.

Process for the preparation of suspensions of drug particles for inhalation delivery

A process for the preparation of compounds of formula (I),

Process for the preparation of aminocarbonyl derivatives of geneseroline having selective brain anticholinesterase activity

A pharmaceutical composition in the form of effervescent tablets comprising an active ingredient and an effervescent blend, wherein the effervescent blend comprises an acidic component and sodium glycine carbonate as alkaline components. Preferred acid components are fumaric acid, maleic acid, and their salts. Tablets are prepared in normal thermo-hygrometric conditions and with standard tabletting equipment.

Strip of containers for liquids or pastes

.alpha.-amino acid amides, preparation thereof and the therapeutical use

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Parma, Italy

Paolo Chiesi