Synarc Inc

Paola Pettersen

Mads Nielsen

Marleen De Bruijne

Claus Christiansen

Erik B Dam

Jenny Folkesson

Ole F Olsen

Michael Lund

A method for the analysis of three dimensional scan data representing an articular cartilage is provided to extract a quantitative parameter indicative of joint pathology. A measure of local curvature of the cartilage is determined within a region of interest. The value of the quantitative parameter of this joint derived from this measure is compared with the value of a similar quantitative parameter previously established in respect of healthy joints and/or joints characterized by a pathology.

Cartilage curvature

A method of deriving an estimate of the extent of fracture in a vertebra shown in an image of part of A spine is provided. The images of at least two vertebrae are segmented to obtain data representative of the shape and size of each of the vertebrae. An approximation of the shape of a first of the vertebrae is reconstructed by comparing the data obtained for a second of the two vertebrae with a mathematical model of at least the same two vertebrae of an unfractured spine. The unfractured shape of the first vertebra is predicted to enable a comparison of the shape and size of the first vertebra as imaged with the predicted unfractured shape and size. The difference between the respective images is subsequently computed to obtain a result representative of the extent of fracture in the first vertebra.

Vertebral fracture quantification

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Koege, Denmark

Paola Pettersen