Honeywell International Inc.

Ativa Medical Corporation

Pamela Wong

Eric Richard Peltola

Phillip Henning

Elizabeth Palaima

Mark A Kelley

Lynn M Seifried

Ron Bardell

Daniel R McPeak

Ka Man Lee

Robert Janisch

Steve Burris

Kylin Hoehn

Apparatus, system and method for dispensing a particle-laden fluid from a fluid holding and dispensing micro-feature and/or multiple lysing channel structures. In some implementations, the apparatus includes: a chamber having one or more surfaces that define a volume to receive fluid containing particulate matter, a soluble surface coating on a portion of the one or more surfaces of the chamber, and an outlet port to dispense at least a portion of the fluid from the chamber. In some implementations, the particle-laden fluid may be whole blood, and the soluble surface coating may include reagents and/or dyes that are diffused into the whole blood received within the chamber to generate signals to visualize various cellular components. In some implementations, the apparatus may also include a second soluble surface coating on portions of surfaces of the multiple lysing channel structures.

Fluid holding and dispensing micro-feature

A multiple polymer layer test cartridge includes an input to receive a sample containing cells, multiple lysing channel structures on alternate layers of the multiple layer test cartridge coupled to each other to pass the sample in sequence between the lysing channel structures, and a test chamber to receive the sample from the multiple lysing channel structures.

Polymer test cartridge mixer for cell lysis

A test cartridge includes an input channel to receive a liquid sample to be tested. A sample chamber is coupled to the input channel to receive the sample. An air permeable membrane is coupled between the sample chamber and ambient to prevent passage of the sample past the membrane and stop movement of the sample in the sample chamber.

Fluid stop for measured sample containment

A disposable blood analysis cartridge may include a sample collection reservoir, an absorbance measurement channel, and an optical light scattering measurement channel. One or more valves may be disposed between the sample collection reservoir and the absorbance measurement channel and/or the optical light scattering measurement channel. A negative pressure may be applied to the cartridge to pull sample from the sample collection reservoir through the one or more valves and into the absorbance measurement channel and/or the optical light scattering measurement channel. Once the sample is pulled into the absorbance measurement channel and/or the optical light scattering measurement channel, the one or more valves may be closed. With the one or more valves closed, and in some cases, a pusher fluid may be provided to push the fluid sample to other regions of the disposable fluid blood analysis cartridge.

Disposable cartridge for fluid analysis

Growing community of inventors

White Bear Lake, MN, United States of America

Pamela Wong