Eastman-kodak Company

The Mclean Hospital Corporation

Paige Miller

David Lynn Patton

Richard N Blazey

Peter A Parks

John Randall Fredlund

Elena A Fedorovskaya

Girish V Prabhu

Richard S Keirsbilck

Cecelia M Horwitz

Jose M Mir

Swatee N Surve

John Joseph Scheible

Laurie Schaefer

Gregory B Foust

Robert W Hopkins

Jose V Mir

Ronald E Swanson

A method for determining the appropriate dosage of a medication to treat Attention Deficit Hyperactivity Disorder (ADHD) in an individual who has ADHD. The method comprises sampling the peripheral skin temperature of left and right like extremities of an individual during a predetermined time interval when the individual is in a sensory deprived state to provide respective left and right sampled peripheral skin temperature data, processing the sampled peripheral skin temperature data; processing the sampled peripheral skin temperature data including filtering, differentiation, and conversion to the frequency domain to derive spectral signatures whose magnitudes are indicative of the level of ADHD manifestation. The effectiveness of the medication is calculated by comparison to predetermined threshold values.

Method and apparatus for determining attention deficit hyperactivity disorder (ADHD) medication dosage and for monitoring the effects of ADHD medication on people who have ADHD using complementary tests

This invention features a method of determining whether an individual has Attention Deficit Hyperactivity Disorder by sampling the peripheral skin temperature of an individual in an inactive state and manipulating the resulting temperature data to produce a value which is indicative of whether or not the individual has ADHD.

Technique for diagnosing attention deficit hyperactivity disorder

A method of determining threshold values, subsequently used to determine whether an individual has Attention Deficit Hyperactivity Disorder (ADHD) comprising: providing a group of subjects, a segment of which is known to have ADHD and a segment is known to not have ADHD; and testing each subject in the group by: (a) sampling the peripheral skin temperature of left and right like extremities during a predetermined time interval when the subject is in a sensory deprived state to provide respective left and right sampled peripheral skin temperature data; (b) processing the sampled peripheral skin temperature data, including filtering, differentiation, and conversion to the frequency domain to derive spectral signatures having magnitude values; and (c) final processing of spectral signatures for all of the subjects of the group to determine threshold values which are complimentarily effective for determining whether or not an individual has ADHD when tested by the testing method.

Technique for diagnosing attention deficit hyperactivity disorder using complimentary tests

A method for determining the appropriate dosage of a medication to treat Attention Deficit Hyperactivity Disorder (ADHD) in an individual who has ADHD comprising: sampling the peripheral skin temperature of a human subject during a predetermined time interval when the subject is in an inactive state to provide sampled peripheral skin temperature data; analyzing the sampled peripheral skin temperature data for a pre-selected parameter to determine whether the pre-selected parameter has a value indicative of ADHD; and determining the proper dosage of a medication to treat ADHD based upon the determined value of the pre-selected parameter. At a time subsequent to administering the dosage, it is determined if a previously administered dosage of a medication is effective at removing the effects of ADHD as measured by this pre-selected parameter.

Method for determining attention deficit hyperactivity disorder (ADHD) medication dosage and for monitoring the effects of (ADHD) medication

A method for determining the appropriate dosage of a medication to treat Attention Deficit Hyperactivity Disorder (ADHD) in an individual who has ADHD. The method comprises sampling the peripheral skin temperature of left and right like extremities of an individual during a predetermined time interval when the individual is in a sensory deprived state to provide respective left and right sampled peripheral skin temperature data; processing the sampled peripheral skin temperature data; processing the sampled peripheral skin temperature data including filtering, differentiation, and conversion to the frequency domain to derive spectral signatures whose magnitudes are indicative of the level of ADHD manifestation. The effectiveness of the medication is calculated by comparison to predetermined threshold values.

METHOD AND APPARATUS FOR DETERMINING ATTENTION DEFICIT HYPERACTIVITY DISORDER (ADHD) MEDICATION DOSAGE AND FOR MONITORING THE EFFECTS OF ADHD MEDICATION ON PEOPLE WHO HAVE ADHD USING COMPLEMENTARY TESTS

A method for determining a threshold value of a parameter used to determine whether an individual has Attention Deficit Hyperactivity Disorder (ADHD). The method includes: providing a group of individuals a segment of which is known to have ADHD and a segment of which is known to be normal and not have ADHD; testing each individual in the group by sampling the peripheral skin temperature of the individual during a pre-determined time interval when the individual is in an inactive state to provide sampled peripheral skin temperature data, and analyzing the sampled peripheral skin data to produce a parameter value for that individual. The method further includes: processing the individual parameter values for all of the members of the group to determine a threshold parameter value which is acceptable for determining whether or not an individual has ADHD when tested by the testing procedure.

A method for determining the appropriate dosage of a medication to treat Attention Deficit Hyperactivity Disorder (ADHD) in an individual who has ADHD comprising: sampling the peripheral skin temperature of a human subject during a predetermined time interval when the subject is in an inactive state to provide sampled peripheral skin temperature data; analyzing the sampled peripheral skin temperature data for a pre-selected parameter to determine whether the pre-selected parameter has a value indicative of ADHD; and determining the proper dosage of a medication to treat ADHD based upon the determined value of the pre-selected parameter.

A method of determining the physiological reactivity of an individual with respect to images, comprising: measuring at least one physiological parameter of an individual during a baseline calm period of time; measuring the said at least one physiological parameter of said individual during a stress period of time and a succeeding rest period of time; dividing said measured data for each of said periods of time into a plurality of predetermined time segments; computing a histogram or Fourier analysis as appropriate on said predetermined time segments for each said period of time; standardizing said computed data; conducting a principal component analysis, a canonical discriminant analysis, or a neural network, on said data to establish a baseline calm or rest period set of scores and a stress period set of scores; measuring the said at least one physiological parameter of said individual during an image presentation period of time; repeating said time segmenting, said histogram or Fourier analysis, and said standardizing steps on said measured physiological data for said image presentation period of time; applying said vectors from said conducting step to said image data to produce an image set of scores which are compared with said baseline and stress sets of scores; and determining whether said presented image is activating, deactivating, or neutral based on said comparison.

Management of physiological and psychological state of an individual using images biometric analyzer

A method of managing a physiological or psychological state of an individual using images comprising: determining an individual's direction or preference for a state management session; based on the determination, deciding whether a current set of images selected through a personal image profile session, will achieve the desired management effect; if the current set are deemed satisfactory, presenting the set of images to the individual to achieve management of the individual's state.

Management of physiological and psychological state of an individual using images overall system

A method of generating a personal image profile based on an individual's physiological and cognitive state compromising: presenting a master set of images to an individual wherein each image in the master set is characterized by a set of scene and image related classifiers that are relevant to producing an effect on an individual; measuring and recording one or more of said individual's physiological parameters while viewing a presented image; measuring the individual's cognitive state from cognitive responses to each presented image; and generating a personal image profile of the individual based on combining the physiological and cognitive measures from said measuring steps, said personal image profile including image classifiers for identifying activating or deactivating images for said individuals.

Management of physiological and psychological state of an individual using images personal image profiler

In a manufacturing process using multivariate analysis for statistical process control, data representing a plurality of process and/or product variables is collected during operation of the process. A surrogate variable, representing the overall state of the process is evaluated. The surrogate variable is a function of a plurality of intermediate variables, which in turn are a function of the process and/or product variables. When the value of the surrogate variable is outside of a predetermined limit, the contributions to the surrogate variable by the intermediate variables are calculated. The intermediate variable with the largest contribution is identified and the contributions to the identified intermediate variable by the process variables is calculated., The process variables with the largest contribution to the identified intermediate variable are identified, and used to diagnose and correct the problem with the process.

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Rochester, NY, United States of America

Paige Miller