Medtronic, Inc.

Boston Scientific Scimed, Inc.

Medtronic Vascular, Inc.

Medtronic Cv Luxembourg S.a.r.l.

Medtronic Vascular Galway Limited

Padraig Savage

Matthew Rust

Finn Olavi Rinne

Gianfranco Pellegrini

Igor Kovalsky

Joshua J Dwork

Michael Lee

Kshitija P Garde

Jason L Quill

Michael Krivoruchko

Nathan K Brown

Kenny Dwight Bruner

Randall T Lashinski

Richard Glenn

Patrick Edward Macaulay

Erik Griswold

Justin Goshgarian

Susheel Deshmukh

Karan Punga

Sarah E Ahlberg

Lance Ensign

Jeffrey D Sandstrom

Philip Jon Haarstad

Lucas Tradd Schneider

Adam Shipley

Kristian Kristoffersen

Matthew Baldwin

Rui Lam

Richard Bliss

Devin Gosal

Billy Tam

Alaena Destefano

Joseph Callol

Joshua Mark Inouye

Stephen Nash

Robert J Murray, Iii

Frank Harewood

Pham Lo

Graham Krumpelmann

Constantin Ciobanu

William Steinberg

Christopher Robert Lashinski

Evin Donnelly

Jordan Skaro

Levi Wolterstorff

Robert Murry, Iii

Giangranco Pellegrini

Joesph Callol

A delivery system for use with a prosthetic heart valve having a stent frame to which a valve structure is attached, includes a shaft assembly including a distal end and a coupling structure disposed near the distal end and configured to be coupled to a distal end of the prosthetic heart valve. The system includes a sheath assembly defining a lumen sized to slidably receive the shaft assembly. The delivery system is configured to transition from a loaded state in which the sheath assembly encompasses the prosthetic heart valve to a deployed state in which the sheath assembly is withdrawn from the prosthetic heart valve. The coupling structure is configured to provide a controlled expansion or contraction of the distal end of the prosthetic heart valve based on longitudinal movement of the distal end of the shaft assembly.

Transcatheter delivery system and method with controlled expansion and contraction of prosthetic heart valve

A tissue anchor for securing an implantable device to tissue such as soft tissue. The anchor includes a tissue-engaging portion having a tissue-engaging configuration which enhances, improves, increases, etc., the engagement, grasp, purchase, etc. of the anchor with the body tissue in which the anchor is implanted. In some embodiments, the tissue-engaging portion cinches or pinches or compresses tissue between sections of the tissue-engaging portion to grab onto or otherwise engage tissue. In some embodiments, a section of the tissue-engaging portion expands or otherwise extends away from the other portions of the anchor to increase engagement of the anchor with the tissue. In some embodiments, a section of the tissue-engaging portion may flare outwardly to drive further into tissue in a direction transverse to other portions of the anchor.

Tissue anchors minimizing migration and maximizing engagement

An anchor assembly having a helical anchor extending through an anchor bore defined in the anchor housing. In some embodiments, at least one helical turn of the helical anchor extends beyond a portion of the anchor bore. In some embodiments, at least one helical turn of the helical anchor extends beyond a side wall of the anchor housing. In some embodiments, the helical turns of the helical anchors of anchor assemblies mounted adjacent one another on an implantable device nest within one another when the implantable device is in an unexpanded configuration. In some embodiments, the distalmost helical turn of the helical anchor has an outer diameter greater than more proximal helical turns of the helical anchor. In some embodiments, the outer diameters of the at least some of the helical turns of the helical anchor taper from a distal end to a proximal end of the helical anchor.

Anchoring devices, systems, and methods for implantable device

Solutions for reducing irritation and/or trauma which may result upon contact of an implanted implantable device with tissue surrounding or adjacent to the implantable device. Various embodiments include features which allow a tangential or otherwise atraumatic contact of the implantable device with the tissue, in contrast with a sharper contact which may occur with prior art implantable devices. The broad principles are applicable to annuloplasty devices, and have other broader applications as well.

Atraumatic components and structures for implantable devices

Features for a restraint to facilitate delivery and deployment of an implantable cardiac device are described. The restraint may include a series of circumferential engagements for securing inwardly corresponding portions of the implant. The restraint may be located inside the implant and provide a radially inward force on the implant. The restraint may include a center shaft having a series of grooves configured to cooperate with corresponding splines of the implant. Distal or proximal advance of the restraint disengages the restraint from the implant. The implant may include a tubular frame configured to contract and be secured by the restraint in a contracted configuration and to expand upon disengagement from the restraint. The restraint may provide for a smaller overall cross-sectional profile of a transcatheter delivery system, for instance by negating the need for a distal delivery sheath.

Delivery system with integrated central restraint for an implantable cardiac device

Systems, devices and methods related to various heart valve implants and for delivery of those implants are described. The implants may be used to re-size a native valve annulus or to replace a native heart valve. The implants include a re-sizable frame having angled struts. The implant is secured to tissue with anchors that can rotate without axial advancement to engage tissue while drawing the implant closer to the tissue. Collars are used to decrease the angle between struts of a frame to contract the implant. The implants can include a rotatable shaft, such as a threaded shaft, located internally to an axially translatable collar. Rotation of the shaft transmits force to the collar to cause the collar to translate axially, closing the angle of adjacent struts and decreasing the width of the implant and thus of the annulus. The implants can be delivered, secured and contracted via a catheter. The implants are repositionable and retrievable via catheter.

Implantable device and delivery system for reshaping a heart valve annulus

A prosthesis can include a collapsible, reexpandable frame comprising first, second, and third sets of struts that define first and second rows of expandable cells. In some embodiments, the struts of the first, second, and third set of struts can be tapered. In some embodiments, the frame can include an intermediate section and an inflow section that is proximal to the intermediate section. The inflow section can include a concave saddle portion that is adjacent the intermediate section, and an outwardly flared portion.

Valve prosthesis frames

Prosthetic heart valve devices and associated methods for percutaneous or transcatheter heart valve replacement are disclosed herein. A heart valve prosthesis configured in accordance herewith includes a frame having a valve support and a plurality of support arms extending therefrom. The plurality of support arms may include a main support arm configured to extend from the valve support for capturing at least a portion of a valve leaflet of a native heart valve therebetween when the valve prosthesis is in an expanded configuration and deployed within the native heart valve. In addition, the plurality of support arms may include multiple supplemental support arms disposed about the circumference of the valve support that when deployed in the expanded configuration are configured to at least partially engage subannular tissue at the native heart valve.

Heart valve prostheses having multiple support arms and methods for percutaneous heart valve replacement

A prosthesis can include a collapsible, reexpandable frame having first, second, and third sets of struts that define first and second rows of expandable cells. In some embodiments, the struts of the first, second, and third set of struts can be tapered. In some embodiments, the frame can include an intermediate section and an inflow section that is proximal to the intermediate section. The inflow section can include a concave saddle portion that is adjacent the intermediate section, and an outwardly flared portion.

A stented valve including a stent structure having a generally tubular body portion, an interior area, a longitudinal axis, an first end, an second end, and an outer surface; at least one outflow barb extending from the outer surface of the stent adjacent to the first end of the stent structure and toward the second end of the stent structure; at least one inflow barb extending from the outer surface of the stent adjacent to the second end of the stent structure and toward the first end of the stent structure; and a valve structure attached within the interior area of the stent structure.

Stents for prosthetic heart valves

Heart valve prosthesis are disclosed that include a frame or support structure having an inflow portion, a valve-retaining tubular or central portion and a pair of support arms. The inflow portion radially extends from a first end of the valve-retaining tubular portion and the pair of support arms are circumferentially spaced apart and radially extend from an opposing second end of the valve-retaining tubular portion.

Heart valve prosthesis

A delivery system for percutaneously deploying a stented prosthetic heart valve. The system includes a delivery capsule and a recapture assembly. The capsule is configured to compressively retain the prosthesis. The recapture assembly includes a frame and sleeve attached to the frame. The recapture assembly is transitionable from a compressed arrangement to an expanded arrangement with a distally increasing diameter.

Transcatheter prosthetic heart valve delivery system with recapturing feature

Growing community of inventors

Santa Rosa, CA, United States of America

Padraig Savage