Other

Hollis-eden Pharmaceuticals, Inc.

- Humanetics Corporation

Harbor Biosciences, Inc.

Padma Marwah

Henry A Lardy

Ashok Marwah

Ashok Kumar Marwah

The instant invention provides potent antiandrogen compounds, such as 3&#x3b2;-acetoxyandrost-1,5-diene-17-ethylene ketal and 3&#x3b2;-hydroxyandrost-1,5-diene-17-ethylene ketal, and methods for their use in the prevention and treatment of biological conditions mediated by androgen receptors. Thus, for example, compounds of the invention are useful in the prevention and treatment of prostrate cancer. Furthermore, it has been discovered that compounds of the invention are useful in the prevention and treatment of androgen-independent cancers such as androgen-independent prostrate cancer. Finally, inventive compounds may be used to treat antiandrogen induced withdrawal syndrome.

Diene and triene compounds and formulations

Diene compounds and formulations

Prostate cancer treatment

Steroids having 1,8-unsaturation and formulations comprising same

A procedure for oxidizing organic compounds having allylic hydrogen atom(s) involving the steps of reactively contacting the organic compound with a combination of a periodic acid or metal periodate and an alkyl hydroperoxide under conditions of normal as well as elevated pressure of a suitable gas like air. The reaction can conveniently be conducted at temperatures between about 0-65&deg; C. in a cosolvent system of water and organic solvent(s).

Process for effecting allylic oxidation

A frilly dental floss formed of thin wide ribbon with frilly edge(s) or centrally located slits or the combination thereof, made from a strong, naturally waxy, polymer material preferably from a biodegradable, thin-gauged high-density polyethylene (HDPE) material.

Frilly dental floss

A procedure for oxidizing organic compounds having allylic hydrogen atom(s) involving the steps of reactively contacting the organic compound with a combination of an N-hydroxy dicarboxylic acid imide and a chromium-containing oxidant. The reaction can conveniently be conducted under ambient temperature and pressure conditions, and is conveniently conducted in a co-solvent system of water and organic solvent(s).

Process for effecting allylic oxidation using dicarboxylic acid imides and chromium reagents

The present invention is directed to a process for effecting the allylic oxidation of an allylic compound having at least two allylic hydrogen atoms on the same carbon atom into corresponding &agr;,&bgr;-unsaturated carbonyl compound, using a combination of a metal hypochlorite and an alkyl hydroperoxide in a mixture of suitable conventional organic solvent(s) and/or water at a temperature of between about &minus;5&deg; C. to &plus;25&deg; C.

Process for allylic oxidation using metal hypochlorite and alkyl hydroperoxide

A pet bathrobe for completely enclosing animal and made of one or more layers of water absorbent material. The bathrobe comprises a rectangular bag having four sides with small openings at both lower corners and an opening extending across entire longitudinal length of the upper side with one end extending into a cap like hood and other end having a small opening. The top opening can be closed with the help of a closure mechanism. The bathrobe may be covered with an optional detachable outer layer made of water impervious material and has a mechanism to hold bathrobe around animal's neck.

Multipurpose bathrobe for pets

A procedure for oxidizing organic compounds having allylic hydrogen atom(s) involving the steps of reactively contacting the organic compound with a combination of a periodic acid or metal periodate and an alkyl hydroperoxide under conditions of normal as well as elevated pressure of a suitable gas like air. The reaction can conveniently be conducted at temperatures between about 0-65.degree. C. in a cosolvent system of water and organic solvent(s).

A procedure for oxidizing organic compounds having allylic hydrogen atom(s) involving the steps of reactively contacting the organic compound with a combination of an alkali metal periodate and an alkyl hydroperoxide. The reaction can conveniently be conducted under ambient temperature and pressure conditions, and is conveniently conducted in a cosolvent system of water and organic solvent(s).

Growing community of inventors

Albany, WI, United States of America

Padma Marwah