University of Massachusetts

University of Virginia Patent Foundation

University of Pennsylvania

Kopf, Gregory S.

Pablo E Visconti

John C Herr

Zhonglin Hao

Felipe Navarrete

Gregory S Kopf

Methods for improving the functionality and/or fertility of sperm, for example, by enhancing motility and/or extending the lifespan of sperm by subjecting the isolated sperm to a starvation protocol and/or ionophore are provided. Such methods may be used in, for example, artificial insemination to reduce the number of sperm needed for insemination and to improve conception rates.

Method to prepare sperm

The present invention relates to a family of testis specific kinases (the tssk family), nucleic acid sequences encoding those kinases and antibodies against the kinases. The invention is further directed to the use of thise kinases as targets for isolating specific inhibitors or anagonists of tssk kinase activity. Such inhibitors are anticipated to have use as contraceptive agents.

Human testis specific serine/threonine kinase 3

The present invention relates to a family of testis specific kinases (the tssk family), nucleic acid sequences encoding those kinases and antibodies against the kinases. The invention is further directed to the use of those kinases as targets for isolating specific inhibitors or antagonists of tssk kinase activity. Such inhibitors are anticipated to have use as contraceptive agents.

Human testis specific serine/threonine kinase 1 and 2

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Amherst, MA, United States of America

Pablo E Visconti