Koninklijke Philips Corporation N.v.

Pablo Andres Ñañez Ojeda

William Anthony Truschel

Francesco Vicario

Michael Polkey

Nikolaos Karamolegkos

A method for controlling a ventilator to provide variable volume (VV) with average volume assured pressure support (AVAPS), including: producing a VV target volume using a VV distribution function; producing a volume error Verror that is the difference between the VV target volume and a measured volume of the previous breath; scaling the volume error Verror; producing a VV target difference as the difference between VV target volume and the VV target volume of the previous breath; producing a modified volume error by adding the VV target difference to the scaled volume error Verror; producing a delta pressure support ΔPS based upon the modified volume error and a dynamic compliance; and producing a current pressure support value based upon the delta pressure support ΔPS and the pressure support value of the previous breath.

Method of delivering variable ventilation with AVAPS

The present disclosure pertains to a system and method for monitoring lung disease in a patient that is based on information that is derivable from home therapy devices including a ventilation therapy device and an oxygen saturation monitor such as a pulse oximeter. The measured parameters are used to model shunt fraction and a volume of dead space. Based on changes in gas exchange and results of a nitrogen washout test, a change in gas exchange impairment in the patient is observed and is then used to determine progression of a disease, identify a cause of the impairment, and/or to guide treatment of the patient.

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MONROEVILLE, PA, United States of America

Pablo Andres Ñañez Ojeda