Wyeth

P Sivaramakrishnan Ramamoorthy

Boyd Lynn Harrison

Robert E McDevitt

Zhongqi Shen

Compounds of Formula I or a pharmaceutically acceptable salt thereof are provided: where Rthrough Rare defined herein. The compounds of Formula I are 5HT2c agonists or partial agonists, and are useful for treating a variety of disorders.

[1,4]diazepino[6,7,1-IJ]quinoline derivatives as antipsychotic and antiobesity agents

3-Amino chroman and 2-amino tetralin derivatives and compositions containing such compounds are disclosed. Such compounds are useful for modulating activity of a 5-HTreceptor (agonizing or antagonizing) in a patient. These compounds are further useful for inhibiting binding to a serotonin receptor. Methods of using the 3-amino chroman and 2-amino tetralin compounds and compositions containing such compounds in the treatment of serotonin disorders, such as depression and anxiety, are also disclosed.

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[1,4]Diazepino[6,7,1-ij]quinoline derivatives as antipsychotic and antiobesity agents

Compounds of Formula I or a pharmaceutically acceptable salt thereof are provided: where Rthrough Rare defined herein. The compounds of Formula I are 5HT2agonists or partial agonists, and are useful for treating a variety of disorders.

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Plainsboro, NJ, United States of America

P Sivaramakrishnan Ramamoorthy