Ganymed Pharmaceuticals Ag

Biontech Ag

Ganymed Pharmaceuticals Gmbh

Tron—translationale Onkologic An Der Universitätsmedzin Der Johannes Gutenberg-Universität Mainz Gemcinnützige Gmbh

Ozlem Türeci

Ugur Sahin

Michael Koslowski

Markus Fiedler

Tim Beissert

Fabrice Le Gall

Christiane Regina Stadler

Arne Jendretzki

Laura Plum

Julia Holland

Hayat Bähr-Mahmud

The present invention provides binding agents that contain n binding domain that is specific for CD3 allowing binding to T cells and a binding domain that is specific for a tumor-associated claudin molecule and methods of using these binding agents or nucleic acids encoding therefor for treating cancer.

Agents for treatment of claudin expressing cancer diseases

The invention relates to the identification of genetic products expressed in association with tumors and to coding nucleic acids for the expressed products. An embodiment of the invention also relates to the therapy and diagnosis of disease in which the genetic products are aberrantly expressed in association with tumors, proteins, polypeptides and peptides which are expressed in association with tumors, and to the nucleic acids coding for the polypeptides, peptides and proteins.

Genetic products differentially expressed in tumors and the use thereof

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Mainz, Germany

Ozlem Türeci