Bayer Aktiengesellschaft

Ozkan Yalkinoglu

Stefan Wohlfeil

Martin Beuck

Johannes-Peter Stasch

Andreas Knorr

Peter Fey

Stanislav Kazda

Ulrich E Muller

Rudolf H Hanko

Matthias Muller-Gliemann

Thomas Kramer

Jurgen Dressel

Walter Hubsch

Claudia Hirth-Dietrich

Dirk Denzer

Christoph Gerdes

James J Elting

Siegfried Zaiss

Stefan Lohmer

Anke Domdey-Bette

Matthias M uller-Gliemann

Ulrich E M Uller

Ulrich Niewohner

Rudi Grutzmann

J Urgen Dressel

Thomas Kr Amer

Walter H Ubsch

Walter Husch

Rudi Gr Utzmann

The phenylcyclohexylcarboxamides, some of which are known, are suitable as active compounds in medicaments, in particular in medicaments for the treatment of restenosis.

Use of phenylcyclohexylcarboxamides

Sulphonylbenzyl-substituted imidazolylpropenoic acid derivatives can be prepared by reacting sulphonylbenzyl-substituted aldehydes with appropriate CH-acidic compounds and then dehydrating. The sulphonylbenzyl-substituted imidazolylpropenoic acid derivatives can be used in medicaments, in particular for the treatment of high blood pressure and atherosclerosis.

Sulphonylbenzyl-substituted imidazolylpropenoic acid derivatives

Substituted indole derivatives are prepared by reacting appropriate carboxylic acids, if appropriate in the presence of auxiliaries, with appropriate amines. The substituted indole derivatives are suitable as active compounds in medicaments, in particular in medicaments for the treatment of arteriosclerosis and restenosis.

Substituted indole derivatives

Sulphonylbenzyl-substituted imidazolypropenoic acid derivatives

Imidazolyl-substituted phenylacetic acid derivatives are prepared by first reacting suitably substituted phenylacetic acid with imidazoles and subsequently converting the product into an amide. The compounds can be employed as active compounds in medicaments, in particular for treating hypertension and atherosclerosis.

Imidazolyl-substituted phenylacetamides

Sulphonylbenzyl-substituted imidazopyridines can be prepared by reacting correspondingly substituted imidazopyridines with sulphonylbenzyl compounds. The sulphonylbenzyl-substituted imidazopyridines can be employed as active compounds in medicaments, in particular for the treatment of hypertension and atherosclerosis.

Sulphonylbenzyl-substituted imidazopyridines

Substituted phenylacetamides can be prepared by reaction of appropriately substituted phenylacetic acids with imidazoles and subsequent amidation. The substituted phenylacetic acid derivatives can be employed in medicaments for the treatment of high blood pressure and atherosclerosis.

Substituted phenylacetamides

Sulphonylbenzyl-substituted imidazoles can be prepared by first reacting imidazolylaldehydes with sulphonylbenzyl compounds and then oxidising or reducing the aldehyde function in the customary manner. The sulphonylbenzyl-substituted imidazoles can be used as active compounds in medicaments.

Sulphonylbenzyl-substituted imidazoles

Sulphonylbenzyl-substituted pyridones can be prepared by reacting pyridones with sulphonylbenzyl compounds. The sulphonylbenzyl-substituted pyridones can be employed as active compounds in medicaments, in particular for the treatment of arterial hypertension and atherosclerosis.

Sulphonylbenzyl-substituted pyridones which are angiotension II receptor

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Ozkan Yalkinoglu