University of Miami

Intelligent Hearing Systems

Ozcan Ozdamar

Jean-Marie Arthur Parel

Fabrice Manns

Rafael E Delgado

Fred Telischi

A microprobe useful for assessing auditory function by enabling clinical and intraoperative measurements of blood flow, particularly cochlear blood flow and neural compound action potentials, particularly of the auditory nerve (cranial nerve VIII) is disclosed. In addition, a monitoring system containing this microprobe and a method of using the microprobe are described.

Otic microprobe for neuro-cochlear monitoring

The evoked potential processing system includes, in one embodiment, a spectral averaging method. Time based, digital pre-stimulus and post-stimulus electroencephalographic (EEG) signal streams are obtained and are converted into frequency spectrum signals. A differential spectrum is obtained. The differential spectrums from a plurality of sweeps are summed. The summed differential spectrum is then converted into a time based signal stream which contains the evoked potential (EP) signal therein. The EP signal can also be obtained utilizing a two-dimensional filter. Pre- and post-stimulus EEG signal streams for a sub-group of stimuli, wherein each stimulus in a group has the same intensity or frequency, are filtered by conventional averaging or spectral differential averaging. The time based, filtered, post-stimulus EEG signal streams are placed in an array and the array is then filtered by a two-dimensional Fast Fourier Transform (FFT) filter. The array is then filtered by a mask and the masked array is then transformed into a time based format by an inverse FFT. The adaptive averaging technique utilizes a computational formula which computes an estimated running signal to noise ratio. When the difference between the pre-stimulus running SNR and the post-stimulus running SNR is less than a predetermined threshold, further stimulation and acquisition of EEG signals stops. Hence, the post-acquisition processing of the EEG signals is limited to that number of EEG sweeps. The electrode wire configuration uses a cross wiring scheme wherein the shield of a particular wire is connected to the other electrode wire to eliminate artifacts in the respective electrode wire.

Growing community of inventors

Miami, FL, United States of America

Ozcan Ozdamar