R.p.scherer Technologies, Inc.

Owen Murray

Patrick Kearney

Richard David Green

Michael Hall

Juha-Matti Savola

Leon Grother

Susan Gerrard Banbury

Walter Lunsmann

Päivi Juujärvi

Improved formulations containing substituted imidazole derivatives of the general formula 1, formula (I) wherein Y is &#x2014;CH&#x2014; or &#x2014;CO&#x2014;, Ris H, halo or hydroxy, Ris H or halo, and Ris H or lower alkyl (e.g. Cto Calkyl, preferably Cor Calkyl), or a pharmaceutically acceptable salt, such as an acid addition salt, e.g. the hydrochloride, of a compound of the general formula (I), are in solid fast-dispersing dosage form suitable for pre-gastric absorption. 

Formulations containing substituted imidazole derivatives

The invention disclosed herein relates to a pharmaceutical composition comprising a carrier and an active ingredient, wherein the carrier is fish gelatin and the composition is a fast-dispersing dosage form designed to release the active ingredient rapidly on contact with a fluid. In one embodiment, the composition is designed for oral administration and releases the active ingredient rapidly in the oral cavity on contact with saliva. The fish gelatin can be obtained from cold water fish sources and is preferably the non-gelling, non-hydrolyzed form. A process for preparing such a composition and a method of using fish gelatin in a fast dispersing dosage form are also provided.

Fast-dispersing dosage forms containing fish gelatin

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Swindon, United Kingdom

Owen Murray