The General Hospital Corporation

Massachusetts Institute of Technology

Siemens Healthcare Gmbh

The Brigham and Women's Hospital, Inc.

Ovidiu Andronesi

Himanshu Bhat

Peter Caravan

Bruce R Rosen

Elfar Adalsteinsson

Carolyn Mountford

Alma Gregory Sorensen

Saadallah Ramadan

Borjan Aleksandar Gagoski

A system acquires MR imaging data of a portion of patient anatomy associated with proton spin lattice relaxation time in a rotating frame using an RF (Radio Frequency) signal generator configured to generate RF excitation pulses and a magnetic field gradient generator configured to generate anatomical volume select magnetic field gradients for phase encoding and readout RF data acquisition. The RF signal generator and the gradient generator are configured to provide a rotating frame preparation pulse sequence comprising at least one of, (a) a T1 spin lattice relaxation in a rotating frame (T1&#x3c1;) preparation pulse sequence of adiabatic pulses comprising modulated RF pulses and modulated magnetic field gradients for slice selection and (b) a T2 spin-spin relaxation in a rotating frame (T2&#x3c1;) preparation pulse sequence of adiabatic pulses comprising modulated RF pulses and modulated magnetic field gradients for slice selection.

System for optimized low power MR imaging

Methods for low-power in vivo localized multi-dimensional correlated magnetic resonance spectroscopy ('MRS') are provided. Low-power adiabaticity is achieved, generally, using gradient-modulated radio frequency pulses for localization and mixing. The provided pulse sequences also provide a mechanism for longitudinal mixing, which significantly increases the efficiency of magnetization transfer and thereby increases signal-to-noise ratio.

Method for two-dimensional correlation magnetic resonance spectroscopy

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Melrose, MA, United States of America

Ovidiu Andronesi