Meiji Seika Kaisha, Ltd.

Other

Maiji Seika Kaisha Ltd.

Osamu Sakanaka

Katsuharu Iinuma

Makoto Ohyama

Yasushi Murai

Shinjiro Sumi

Masaaki Takahashi

Peter Jeschke

Norbert Mencke

Achim Harder

Gerhard Bonse

Ken Nishihata

Yumiko Okada

Makoto Taniguchi

Katsuharau Iinuma

Katsufumi Sebata

Shouhei Yasuda

Yoshiya Shigematsu

Yashushi Murai

Seiji Shibahara

Masao Koyama

Kazumi Yamamoto

Toshio Yoneta

Takayoshi Tamura

Takeshi Teraoka

Keiichi Imamura

Masayuki Takagi

Tadaaki Okada

Haruki Mikoshiba

Maki Matsumoto

Kikuko Kuzuhara

Takashi Teraoka

Maki Ohishi

Natsuko Yamada

Kouichi Mitomo

Koichi Mitomo

Disclosed are novel compounds useful for prevention or control of diseases derived from fungi, a process for producing the same, and novel antifungal agents using the novel compounds. The compounds useful for prevention and treatment of diseases derived from fungi according to the present invention include novel compounds represented by formula (I). The compounds represented by formula (I) have potent antifungal activity against diseases derived from fungi, and do not have phytotoxicity to mammals and agricultural and garden plants, from which diseases should be eliminated, and, even when applied to agricultural and garden plants, have high photostability. wherein

Antifungal compound and process for producing the same

Disclosed are novel compounds useful for the control of harmful organisms, harmful organism control agents using the same, and processes for producing the novel compounds. The useful novel compounds according to the present invention include compounds represented by formula (1). The compounds represented by formula (1) have potent activity against harmful organisms, and do not have phytotoxicity against agricultural and gardening plants, as objects to which the compounds of the present invention are applied for preventive and exterminating purposes, and human beings and beasts wherein A represents a bond or an optionally substituted alkylene chain; Rrepresents one or more groups, which may be the same or different, selected from the group consisting of a hydrogen atom, alkoxy, and haloalkoxy; Rrepresents a hydrogen atom, benzyl, alkyl or alkanoyl, in which the groups other than the hydrogen atom may be substituted; and Rrepresents a hydrogen atom, cycloalkyl, cycloalkenyl, aryl or a heterocyclic group, in which the groups other than the hydrogen atom may be substituted, excluding the case where Rrepresents a hydrogen atom, A represents a bond or a methylene chain, and Rrepresent phenyl or cyclohexyl, and the case where A represents an alkylene chain and Rrepresents a hydrogen atom.

Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component

Novel derivatives of PF1022 substance, which are cyclodepsipeptides represented by the general formula (I) shown below or their salts are useful as anthelmintic agent for prevention or treatment of parasitic infections.

Derivatives of cyclodepsipeptide PF1022 substance

The present invention relates to cyclic thiodepsipeptides, in particular 18 to 24-membered cyclothiodepsipeptides, their endoparasitical compositions, and methods of making and using the same.

Thiodepsipeptides for combating endoparasites and a method for producing the same

Known cyclic depsipeptides which are PF 1022F substance and PF 1022H substance, as well as a novel cyclic depsipeptide, PF 1022G substance, are now prepared simultaneously by cultivating a fungal strain capable of producing PF 1022F substance, PF 1022G substance and PF 1022H substance represented by the known PF 1022 strain (deposited under FERM BP-2671) which is a kind of fungus belonging to asporous imperfect fungi (the order Agonomycetales) and is presumable to belong to the genus Xylaria or the genus Rosellinia in the family Xylariaceae. The PF 1022G substance has the formula: ##STR1##

Cyclic depsipeptide PF 1022G

Preparation of cyclic depsipeptide compounds and a novel cyclic

Derivatives of cyclodepsipeptide PF 1022

New compounds are disclosed having the general formulas (1) and (2): ##STR1## Also described is a process for preparing the compounds of formulas (1) and (2). Further described is a process for preparing a cephalosporin derivative having formula (5): ##STR2## by converting the compound of formula (1) to the compound of formula (2) and then converting the compound of formula (2) to the compound of formula (5).

Azetidinone derivatives and method for producing azetidinone and

Method for producing azetidinone and cephalosporin derivatives

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Odawara, Japan

Osamu Sakanaka