Shiseido Company, Limited

Osamu Moro

Toshihiko Nakane

Hiroshi Fukui

Tomiyuki Nanba

Masaru Suetsugu

Kazuhisa Ohno

Jiro Kishimoto

Masato Hatao

Masumi Koishi

Minoru Fukuda

Eiichiro Yagi

Shigenori Kumagai

Hiroyuki Yokoyama

Hirofumi Aoki

Shuya Tamaki

Yutaka Okunuki

Tadao Ohta

Toshihide Ebisawa

Susumu Takada

Fujihiro Kanda

Yoshio Yahata

Toshihiro Tanaka

Tsunehiko Iwai

The present invention provides a skin test method for predicting the formation of spots in the skin. This method is characterized by judging skin to be susceptible to spot formation in the case expression of genes consisting of MLSTD1, MOGAT1, FADS2, FADS1, HSD3B1, ELOVL3, BG1, PECR, FABP7, FA2H, HAO2, ALOX15B, PDE6A, LZTS1, SEC14L4, BAMBI, CIDEA, TERE1, GAL, THRSP, INSIG1 or CUTL2 in the epidermis is accelerated, or the expression of genes consisting of RBBP6, MSMB, WIF1, ANKRD12, FLG, SYNE2, SCEL, NKTR or AMBP in the epidermis is decreased as compared with normal expression in the epidermis.

Method of predicting spot formation on the skin using spot site-accelerating genes as an indicator thereof and method of screening inhibitors of spot formation on the skin

An aerosol composition containing a composite powder and one or more of propane, isobutane, n-butane and a liquefied petroleum gas (i.e., LPG) which is a mixture thereof, a chlorinated hydrocarbon and dimethyl ether.

Aerosol composition

A magnesium aluminometasilicate coated composite powder which comprises magnesium aluminometasilicate, or magnesium aluminometasilicate and at least one other powder coated on a surface of a core powder and which is usable in, for example, a skin treatment agent, decodorant, and oral composition.

Magnesium aluminometasilicate coated composite powder and use thereof

Growing community of inventors

Yokohama, Japan

Osamu Moro