Konica Minolta, Inc.

Konica Minolta Advanced Layers, Inc.

Osamu Kashiwazaki

Yuichi Atarashi

Naoki Izumiya

In order to calculate and specify a valley wavelength easily and in a short period of time, a detection device for intermolecular interaction is disclosed that is equipped with a detector provided with a ligand, a white light source that irradiates the detector with white light, a spectrometer that detects the light reflected from the detector, and a control device that controls the white-light source and the spectrometer, wherein the aforementioned control device obtains a reflection spectrum by calculating the reflectivity over a fixed wavelength interval, approximates the aforementioned reflection spectrum as a high-dimensional function, selects a wavelength interval comprising the minimum reflectivity from the aforementioned high-dimensional function, approximates the aforementioned high-dimensional function with the aforementioned wavelength interval as a quadratic function of a lower order, and obtains a solution by which the aforementioned quadratic function is differentiated with respect to the wavelength and the value thereof becomes 0.

Detection method for intermolecular interaction and detection device thereof

In order to improve the detection accuracy of a reflection spectrum, a detection device for intermolecular interaction is provided with a detector () which has a ligand (), a white light source () which emits white light, a spectroscope () which detects the spectral intensity of received light, a light transmission unit () which has a first light transmission path () for transmitting the white light from the white light source to the detector, a second light transmission path () for transmitting reflected light of the white light from the detector to the spectroscope, and a third light transmission path () for transmitting the white light from the white light source to the spectroscope, a switching unit () which performs switching between a reflected light receiving state in which the transmission of the reflected light of the white light in the detector to the spectroscope via the first and second light transmission paths is enabled and a white light receiving state in which the transmission of the white light from the white light source to the detector via the third light transmission path is enabled, and a control unit () which controls the switching unit and the spectroscope to perform control for detecting the spectral intensities in the white light receiving state and the reflected light receiving state, respectively.

Growing community of inventors

Hachioji, Japan

Osamu Kashiwazaki