Euglena Co., Ltd.

Osamu Iwata

Kengo Suzuki

Ayaka Nakashima

Yuta Asayama

Eriko Yoshida

Yoshihisa Nakano

Misa Ohgushi

Naoki Harada

Provided are an inhibitor, a prophylactic, and a therapeutic agent for rheumatoid arthritis that have no side effects and that can correct immune abnormality associated with rheumatoid arthritis. The inhibitor, the prophylactic, and the agent for rheumatoid arthritis contain a-derived material as an active ingredient. The inhibitor, the prophylactic and the agent are used as an antirheumatic drug for controlling the activity of rheumatoid arthritis by alleviating immune abnormality associated with rheumatoid arthritis. The inhibitor, the prophylactic, and the agent are also used for a living individual who has not been definitively diagnosed with rheumatoid arthritis. The inhibitor, the prophylactic, and the agent are continuously administered to the living individual from any point before definitive diagnosis of rheumatoid arthritis to any point after the definitive diagnosis. The-derived material is at least one material selected from the group includingalgae, paramylon derived from the, water-soluble amorphous paramylon prepared by treating the paramylon with alkali and neutralizing the treated paramylon, and emulsion paramylon prepared by ejecting a solution of the paramylon from a narrow bore nozzle at a very high pressure to cause the solution to collide with a collision surface.

Suppressive agent for rheumatoid arthritis, prophylactic agent for rheumatoid arthritis, therapeutic agent for rheumatoid arthritis, and food for suppressing rheumatoid arthritis

Provided are a novel renal failure progression inhibitor, prophylactic agent for renal failure, and indoxyl sulfate production inhibitor, intended for human use, in particular, for a patient with renal failure. The renal failure progression inhibitor, prophylactic agent for renal failure, and indoxyl sulfate production inhibitor each comprises paramylon derived fromor a processed product thereof as an active ingredient. In the case of the renal failure progression inhibitor, for example, paramylon is continuously orally administered to a patient suffering from chronic renal failure, undergoing a dialysis therapy, several times per day in a dose of 1 to 5 g per intake. In particular, the renal failure progression inhibitor is singly administered to the patient in a capsule or powdered preparation at a prescribed time interval before and after administration of other drugs.

Renal insufficiency progression inhibitor, prophylactic agent for renal insufficiency and indoxyl sulfate production inhibitor

Provided are a prophylactic or therapeutic agent for a peptic ulcer, a food additive for prevention and treatment of a peptic ulcer, an iNOS expression inhibitor, and a COX-2 expression inhibitor, all of which have little side effects. The prophylactic or therapeutic agent contains a-derived material as an active ingredient. The-derived material may be, paramylon, or an acid-treated paramylon. The prophylactic or therapeutic agent is useful for the prevention or treatment of a peptic ulcer induced by psychological stress. The peptic ulcer may be a gastric ulcer. The food additive contains a-derived material as an active ingredient.

Prophylactic or therapeutic agent for peptic ulcer, food additive for prophylactic or therapeutic use, iNOS expression inhibitor and COX-2 expression inhibitor

Growing community of inventors

Yokohama, Japan

Osamu Iwata