Insight Strategy Marketing Ltd.

Oron Yacoby-Zeevi

Iris Pecker

Maty Ayal-Hershkovitz

Daphna Miron

Yoav Peleg

Hanna Ben-Artzi

Ayelet Gilboa

Haim Moskowitz

Yinon Shlomi

Madelene Mimon

Yinon Schlomi

Madlene Mimon

Bacterial, yeast and animal cells and methods for overexpressing recombinant heparanase in cellular systems, methods of purifying recombinant heparanase therefrom and modified heparanase species which serve as precursors for generating highly active heparanase by proteolysis.

Genetically modified cells and methods for expressing recombinant heparanase and methods of purifying same

A preparation containing an enzymatically inactive form of heparanase, said enzymatically inactive form of heparanase being cleavable into an enzimatically active form of heparanase.

A method of rendering a surface protected bacteria more susceptible to an anti-bacterial agent effected by subjecting the bacteria to a glycosaminoglycans degrading enzyme.

Compositions including glycosaminoglycans degrading enzymes and use of same against surface protected bacteria

A method of managing a patient having an accumulation of mucoid, mucopurulent or purulent material containing glycosaminoglycans, the method comprising the step of administering at least one glycosaminoglycans degrading enzyme to the patient in an amount therapeutically effective to reduce at least one of the following: the visco-elasticity of the material, pathogens infectivity and inflammation. An article of manufacture comprising an inhaler including, as an active ingredient, at least one glycosaminoglycans degrading enzyme for generating aerosols including the enzyme for management a patient having an accumulation of mucoid, mucopurulent or purulent material containing glycosaminoglycans.

Use of glycosaminoglycans degrading enzymes for management of airway

Growing community of inventors

Meitar, Israel

Oron Yacoby-Zeevi