Reva Medical, Inc.

Advanced Cardiovascular Systems, Inc.

Abbott Cardiovascular Systems, Inc.

Orlando M Padilla

Eric V Schmid

Andrew Morris

John Dang Nguyen

Syed F A Hossainy

Daryush Mirzaee

Thomas R Jackson

Robert F Eisele

Steven C Howard

Daniel Moore

Philip Simpson

Joan Zeltinger

Fuh-Wei Tang

John Francis Boylan

Christopher J Tarapata

Keith Allen Esser

Timothy A Limon

Daniel L Cox

David G Matsuura

Walter Dean Gillespie

E Tina Cheng

Kenny L Dang

Donald K Brandom

Andreina P Gomez

Steve Bigus

Joseph Anthony DiPari

Brent Belding

Suzanne Wallace George

John D Nguyen

The invention relates to an expandable stent comprising circumferentially adjacent modules. The modules comprise longitudinally adjacent slide-and-lock radial elements which permit one-way sliding of the radial elements from a collapsed diameter to an expanded/deployed diameter, but inhibit radial recoil from the expanded diameter.

Slide-and-lock stent

A composite stent and a method for making the same are provided.

Composite stent with regioselective material

The invention relates generally to expandable medical implants for maintaining support of a body lumen and, in particular, to an axially nested, diametrically expandable, slide and lock vascular device for enlarging an occluded portion of a vessel. The axially nested vascular device desirably achieves both competitive crossing profiles while maintaining other key features, such as, for example, radial strength and luminal patency. The collapsed profile can also be made very thin without compromising radial strength. Thus, the vascular device can advantageously be deployed in small and difficult to reach areas or vessels. The axial nesting substantially eliminates radial overlap between mating structural elements thereby desirably allowing for a low, uniform profile.

Axially nested slide and lock expandable device

Expandable medical implants for maintaining support of a body lumen are disclosed. Some embodiments of these implants comprise a circumferentially nested, diametrically expandable, moveable vascular device for enlarging an occluded portion of a vessel. The device can be configured to allow for motion such as rotating, translating, and/or slide and lock.

Circumferentially nested expandable device

An intraluminal, balloon expandable stent for implantation in a body lumen is disclosed. The present invention provides a lumen support stent with an unobstructed through-lumen for use in a blood vessel. A constraining mechanism is provided for securely maintaining the stent in the collapsed condition during delivery. The stent is preferably formed with a series of interconnected slide and lock mechanisms for permitting movement from a collapsed condition to an expanded condition and inhibiting radial recoil from the expanded condition. The stent may be formed from a shape memory alloy for providing crush-recovery after deployment.

Balloon expandable crush-recoverable stent device

Methods for forming a composite stent with regioselective material

A strut assembly to be used in conjunction with an embolic filtering device has varying strut thicknesses, with the thickness selected based at least in part on the flexing characteristics of the particular portion of the strut assembly. The strut assembly is formed with patterns having flexing portions and stable portions, with the flexing portions contributing to the flexibility of the strut assembly during delivery and recovery in the patient's vasculature. The stable portions remain relatively unflexed and stiff when being delivered or recovered from the patient's vasculature. The stable portions provide strength and increased radiopacity to the strut assembly which is needed when the strut assembly is deployed in the body vessel. The flexing portions act much like a mechanical hinges in providing the needed flexibility to resiliently bend when being delivered through tortuous anatomy of the patient.

Variable thickness embolic filtering devices and methods of manufacturing the same

Expandable medical implants for maintaining support of a body lumen are disclosed. These implants comprise a circumferentially nested, diametrically expandable, moveable vascular device for enlarging an occluded portion of a vessel. The device can be configured to allow for motion such as rotating, translating, and/or slide and lock. One advantage of the circumferentially nested stent is that it maintains the expanded size, without significant recoil.

Variable thickness embolic filtering devices and method of manufacturing the same

Composite stent with regioselective material and a method of forming the same

The present invention provides a lumen support prosthesis composed of interlocking radial modules which is fabricated fully assembled from a signal piece shape, without welding or bonding. The prosthesis comprises at least one locking mechanism, allowing for one-way sliding of the radial modules and expansion of the prosthesis from a collapsed state, but inhibits radial recoil from the expanded diameter. The prosthesis may be fabricated from biologically degradable materials which have certain medical advantages.

Method of manufacturing a prosthesis

A composite stent and methods for making the same are provided. In one embodiment a regioselective band is formed in situ on the stent. In one embodiment, the band is made of a regioselective material having a high creep compliance and having a second modulus of elasticity lower than that of a structural material comprising the stent. In one embodiment, the regioselective material is drip-coated or dip-coated on the stent near the ends. In one embodiment, the regioselective material includes a therapeutic agent, which may be a radioactive emitter, an anti-platelet drug, or an anti-proliferative drug.

Growing community of inventors

Laguna Niguel, CA, United States of America

Orlando M Padilla