Collplant Ltd.

Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.

Fulcrum Sp Ltd.

Or Dgany

Oded Shoseyov

Daniel L Siegel

Hanan Stein

Amnon Wolf

Amit Yaari

Ira Marton

Yehonathan Pouny

Arie Altman

Michal Rosenthal

Tamar Haya Tal

A method of promoting wound healing, treating fibrosis and/or promoting angiogenesis is provided. The method comprises administering to a subject in need thereof a therapeutically effective amount of a procollagen, thereby promoting wound healing, treating fibrosis and/or promoting angiogenesis in the subject.

Methods of generating and using procollagen

SP1 and modified SP1 variant polypeptides capable of forming reversible molecular associations with substances, compositions-of-matter comprising same, and uses thereof are provided.

Sp1 polypeptides, modified Sp1 polypeptides and uses thereof

A method of generating atelocollagen is disclosed. The method comprises contacting a human telopeptide-comprising collagen with a protease selected from the group consisting of neutrase, subtilisin, ficin recombinant human trypsin and recombinant human pepsin, wherein said human telopeptide-comprising collagen is expressed in a non-animal cell, thereby generating the atelocollagen. Compositions comprising the atelocollagen generated thereby are also disclosed.

Methods of processing recombinant procollagen

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Ashdod, Israel

Or Dgany