Univerzita Palackeho V Olomouci

Ondrej Plihal

Miroslav Strnad

Karel Dolezal

Jiri Voller

Lucie Plihalova

Marek Zatloukal

Lukas Spichal

Jitka Vostalova

Jitka Ulrichova

Alena Rajnochova Svobodova

Alena Kadlecova

Radoslav Koprna

Hana Vylicilova

Ponnusamy Baskaran

Aloka Kumari

Adeyemi Oladapo Aremu

Magdalena Bryksova

Tomas Gucky

Tomas Pospisil

Martin Hönig

Johannes Van Staden

Frantisek Skarupa

Adenine derivatives substituted at the C2, N6, and N9 purine positions having antisenescent and combined photoprotective UVA/UVB effects. These substances are particularly suitable as anti-senescent and UV-photoprotective component in cosmetic preparations, plant protection preparations and in preparations for the treatment/application of tissue cultures. 

Adenine derivatives and their use as UV-photoprotective agents

6-aryl-9-glycosidpurines of general formula I and pharmaceutically acceptable salts thereof with alkali metals, ammonia, amines, or addition salts with acids, wherein

6-aryl-9-glycosylpurines and use thereof

6-aryl-9-glycosidpurines of general formula I and pharmaceutically acceptable salts thereof with alkali metals, ammonia, amines, or addition salts with acids, whereinGly represents &#x3b2;-D-arabinofuranosyl or &#x3b2;-D-2'-deoxyribofuranosyl,Ar represents benzyl or furfuryl, each of which can be unsubstituted or substituted by one or more, preferably one to three, substituents selected from the group comprising hydroxyl, alkyl, halogen, alkoxy, amino, mercapto, carboxyl, cyano, amido, sulfo, sulfamido, acyl, acylamino, acyloxy, alkylamino, dialkylamino, alkylmercapto, trifluoromethyl, trifluoromethoxy, for use as antisenescent and UV protective compounds in animals.

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Olomouc, Czechia

Ondrej Plihal