University of Minnesota

Synerfuse, Inc.

Embomedics, Inc.

Omid Souresrafil

Gregory F Molnar

Harry A Puryear

Nazmi Peyman

Timothy J Cox

Jafar Golzarian

Lihui Weng

Serafin Y Samson

The present disclosure describes a plurality of microspheres that include carboxymethyl chitosan (CCN) crosslinked with carboxymethyl cellulose (CMC). The microspheres are biocompatible, bioresorbable, and biodegradable. The microspheres may be used in personal care products, such as, for example, toothpaste, topical pain relief products, topical antibiotic products, skincare products such as anti-wrinkle products, eczema products, skin scrubs, acne cleansers, exfoliators, body washes, soaps, pre-shave creams, or the like.

Biodegradable microspheres

Radio frequency (RF) energy is transmitted through the application of a RF signal to an external RF energy interface, where the RF signal oscillates at a frequency in an energy transmission band. The transmitted RF energy is received at an implanted medical device, and energy derived from the received RF energy is stored in a direct current (DC) energy storage component of the device. A therapeutic output signal is generated from the stored energy and delivered by the implantable medical device to a patient through one or more electrodes. The therapeutic output signal is configurable to provide either one of RF stimulation therapy and RF ablation therapy, and comprises pulses of an RF signal oscillating at a frequency in a therapy band that is greater than the energy transmission band.

Systems, devices and methods that affect neural tissue through the delivery of a pulsed radio frequency signal generated by an implantable medical device

Growing community of inventors

Maple Grove, MN, United States of America

Omid Souresrafil