Leland Stanford Junior University

Omer Oralkan

Butrus Thomas Khuri-Yakub

Gordon S Kino

Olav Solgaard

Michael J Mandella

Christopher H Contag

Amin Nikoozadeh

Morten Fischer Rasmussen

Kamyar Firouzi

Kim Butts Pauly

Jae Eun Hwang

Patrick Ye

Hyejun Ra

Stephen A Baccus

Michael D Menz

Jae-Woong Jeong

Paul Cristman

Jonathan T C Liu

Improved acoustic neurostimulation is provided by having two or more acoustic transducers generate an acoustic interference pattern in a region of a patient being treated. The apparatus has at least two operating modes it can switch between. A first operating mode has the transducers driven at the same frequency. A second operating mode has the transducers driven at different frequencies. Full control of the acoustic transducers allows the acoustic interference pattern to be varied electronically at will.

Pattern interference radiation force (PIRF) neural stimulators

Aspects of the present invention are directed to apparatuses, arrangements, systems and methods for collecting information using one or more modalities. As consistent with one or more embodiments, an apparatus includes first and second scanning mirror arrangements having different scanning axes and respectively facing different directions. The first scanning mirror arrangement directs source light and image light in two paths, and the second scanning mirror arrangement directs image light from a target to the first scanning mirror arrangement. The first and second scanning mirror arrangements cooperatively scan source light from the first scanning mirror and via the second scanning mirror to target locations with at least two degrees of freedom, and direct image light from the target locations.

Confocal microscope, system and method therefor

As may be implemented in accordance with one or more embodiments, an apparatus and/or method involves a plurality of transducer elements that convert energy waves conveyed via a multi-directional radiation pattern into electrical charge. A power-accumulation circuit accumulates electrical charges from each of the plurality of transducer elements, with each of the transducer elements being arranged at different respective off-axis angles relative to an axis at which the energy is being conveyed. The power-accumulation circuit accumulates energy from each of the individual energy-transduction areas, such that energy received at different respective off-axis angles contributes to the accumulation of electrical charge.

Energy harvesting

The current invention provides an ultrasound-assisted delivery device, that includes a focused ultrasound transducer having an ultrasound focal point, a real-time imaging device having an imaging focal point, and a therapeutic delivery device, where the transducer and the imaging device are integrated with the delivery device, and the ultrasound focal point coincides with the imaging focal point, where the delivery device and transducer are disposed to provide an unobstructed imaging path for the real-time imaging device. The invention further includes a scanning optical or laser beam having a focal point disposed to sweep across the target, where the delivery device is disposed to deliver an optical contrast material to the target, and the scanning focal point coincides with the ultrasound and imaging focal points, where the target or the optical contrast material react to the scanning beam to generate at least one interface signal.

Method and apparatus for ultrasound assisted local delivery of drugs and biomarkers

Surface selective photoacoustic (PA) medical imaging is introduced. Surface selective PA imaging is responsive to surface features and does not image sub-surface features, in contrast to conventional PA imaging. The surface PA signal can be considerably larger than the bulk PA signal, for an air-coupled (or gas-coupled) acoustic transducer. Distinguishing these two signals based on time of arrival at the transducer can further distinguish the two signals. This approach provides numerous advantages. Non-contact imaging simplifies and expedites imaging, and can serve as a replacement for visual inspection by physicians. Applications include skin screening and endoscopy.

Medical screening and diagnostics based on air-coupled photoacoustics

Growing community of inventors

Morrisville, NC, United States of America

Omer Oralkan