Innoplexus Ag

Om Sharma

Vatsal Agarwal

Gaurav Tripathi

Ansh Gupta

Vivekanand Patil

Sandhya V

Manoj Kumar

Priyam Singh

Ishita Mallick

Adity Shandilya

Dinesh Solanke

Amit Choudhari

Anurag Chandrekar

Deepak Sharma

Vijay Singh

Pulkit Anupam Srivastava

Hari Kapa

There is disclosed an Artificial Intelligence (AI) assisted drug discovery system and a method for generating active and inactive targets for a given drug. The generated targets comprise the complete target landscape for the given drug. The system comprises a processor which is configured to train a multi-label deep learning neural network and a predictive model to generate and validate a prediction score, and further execute the trained multi-label deep learning neural network and the trained predictive model to identify targets associated with the given drug, and generate the active and inactive targets for the given drug molecule in response to the generated prediction score for each target associated with the given drug.

System for prediction of the drug target landscape for therapeutic use and a method thereof

A system and method for identifying potential targets for a pharmaceutical compound. The system includes a database arrangement operable to store existing data sources and information related to the pharmaceutical compound; and a processing module communicably coupled to database arrangement. The processing module is operable to receive information related to the pharmaceutical compound, wherein the information includes at least one known target associated with the pharmaceutical compound; extract plurality of targets from existing data sources, wherein the existing data sources comprise plurality of data records and wherein each of the plurality of targets is associated with the pharmaceutical compound in at least one data record; analyse druggability of each of plurality of targets to determine a preliminary set of targets; determine net score for each of the targets in preliminary set of targets; and designate targets with a net score above a predefined threshold, as potential targets.

System and method for identifying potential targets for pharmaceutical compound

A phosphoinositide 3-kinase inhibitor for use in the treatment of pancreatic cancer and a method for treatment of pancreatic cancer including administration of an phosphoinositide 3-kinase inhibitor an Src inhibitor to a human subject in need thereof. There is also provided a pharmaceutical composition comprising a phosphoinositide 3-kinase inhibitor and an Src inhibitor.

Phosphoinositide 3-kinase and Src inhibitors for treatment of pancreatic cancer

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Maharashtra, India

Om Sharma