University of California

The United States Government As Represented by the Department of Veterans Affairs

The Regents Ot the Univershy of California

Olulanu H Aina

Kit S Lam

Chong-Xian Pan

Hongyong Zhang

The present invention is directed to bladder cancer specific ligand peptides, comprising the amino acid sequence XDGRXGF (SEQ ID NO: 1), and methods of their use, e.g., for imaging detection for diagnosis of bladder, tumor localization to guide transurethral resection of bladder cancer, imaging detection of bladder cancer for follow-up after the initial treatment that can replace or complement costly cystoscopy, imaging detection of metastatic bladder cancer, and targeted therapy for superficial and metastatic bladder cancer.

Bladder cancer specific ligand peptides

The present invention is directed to bladder cancer specific ligand peptides, comprising the amino acid sequence XDGRXGF (SEQ ID NO:1), and methods of their use, e.g., for imaging detection for diagnosis of bladder, tumor localization to guide transurethral resection of bladder cancer, imaging detection of bladder cancer for follow-up after the initial treatment that can replace or complement costly cystoscopy, imaging detection of metastatic bladder cancer, and targeted therapy for superficial and metastatic bladder cancer.

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Elk Grove, CA, United States of America

Olulanu H Aina