Novo Nordisk A/s

Institut National De La Recherche Agronomique

Oluf Borbye Pedersen

Lars Bohn Hansen

Torben Stroem Hansen

Stanislav Ehrlich

Emmanuelle Le Chatelier

Christian Bjo Slashedrbae Buttedk

Patricia Townsend Cohen

Kathrine Almind Frederiksen

Carsten Bo Andersen

The present invention relates to a mutant cDNA sequence encoding the regulatory p85.alpha. subunit of phosphatidylinositol 3-kinase (PI3K), a method of detecting a mutation in the gene encoding the regulatory p85.alpha. subunit of phosphatidylinositol 3-kinase, as well as a diagnostic composition and a test kit for use in the method.

Mutant cDNA encoding the p85.alpha. subunit of phosphatidylinositol

The present invention relates to a mutant DNA sequence encoding protein phosphatase 1 G-subunit, wherein a mutation of G to T occurs in the position of codon 905 of the coding sequence, a method of detecting a mutation in the gene encoding protein phosphatase 1 G-subunit, as well as a diagnostic composition and a test kit for use in the method.

Mutant DNA encoding protein phosphatase 1 G-subunit

Mutant DNA encoding insulin receptor substrate 1

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Holte, Denmark

Oluf Borbye Pedersen