Pierre Fabre Dermo-cosmetique

Olivier Sorg

Jean-Hilaire Saurat

Pascal Bordat

Roger Tarroux

Stéphane Poigny

Jean-Louis Brayer

Sylvie Daunes-Marion

Françoise Belaubre

Bernard Fabre

Mathieu Leti

Patrick Bogdanowicz

Natacha Frison

Daniel Bacqueville

Behrooz Kasraee

Francoise Belaubre

The present invention relates to the combination of a retinoid and an extract of(L.) Gaertn., the dermatological and dermocosmetic compositions containing such a combination, as well as their uses as a medicinal product, in particular in the treatment of acne, seborrhea, seborrhoeic dermatitis and/or rosacea.

Combination of a retinoid and an extract of(L.) gaertn

The present invention relates to a(L.) Gaertn. extract comprising less than 0.2% by weight of silymarin with respect to the weight of the dry extract, as well as pharmaceutical and cosmetic compositions containing same, the preparation method thereof and uses thereof as a medicinal product, particularly in the treatment of acne, seborrhoea, seborrheic dermatitis and/or rosacea.

Methods for treating in dermatology and dermo-cosmetics by administeringachene extract

The invention concerns topical compositions based on retinaldehyde, glycylglycine oleamide and, if necessary, delta-tocopheryl-glucopyranoside, and their use in cosmetology and dermatology to combat skin ageing and more particularly light-induced skin ageing.

Cosmetic or dermatological compositions combining cosmetiques retinaldehyde and glycylglycine oleamide and the cosmetic or dermatological uses thereof

The present invention relates to a cosmetic or pharmaceutical composition for cutaneous application, whose goal is the depigmentation of the skin.

Use of delta-tocopheryl-carbohydrate as a depigmenting agent

The invention concerns the cosmetic or dermatological use of at least one compound of formula (I), wherein: R, R, R, R, Rand G are such as defined in the description as whitening and/or depigmenting agents for the skin and/or hairs and/or the hair. The invention also concerns a cosmetic method for whitening and/or lightening the skin and/or hairs and/or the hair comprising applying a composition of the invention. 

Use of polyunsaturated compounds as whitening agents

The invention concerns novel polyunsaturated compounds of formula (I) wherein: Rrepresents a R', -A-R&#x2032;group, R&#x2032;being selected from &#x2014;COOH, &#x2014;COOR, &#x2014;CONH, &#x2014;CONHR, &#x2014;CONRR, &#x2014;CHO, &#x2014;CHOH, &#x2014;CHOR, and A represents a C-Calkylene, alkenylene or alkynylene; Rrepresents: an optionally substituted aryl group or an optionally substituted heteroaryl group; a sugar residue or, a fatty acid residue optionally branched and/or substituted preferably at the chain terminus and particularly by hydroxy, acetoxy radical or by an optionally protected amino radical; a &#x2014;OC &#x2014;(CH)n CO-tocopheryl (alpha, beta or gamma or delta) group, with 2 $m(F) n $m(F) 10; a &#x2014;R&#x2032;&#x2014;O&#x2014;Rgroup, wherein R&#x2032;is an optionally substituted arylene group or an optionally substituted heteroarylene group, and Rrepresents a hydrogen atom, a straight or branched optionally substituted C-Calkyl, a straight or branched optionally substituted C-Calkenyl, or a straight or branched C-Calkynyl group, an optionally substituted tocopheryl radical or the like, an amino acid residue, or a sugar residue. The invention also concerns the compositions, in particular cosmetic and/or dermatological compositions containing at least one compound of formula (I) as well as their use as whitening and/or depigmenting agent, and the cosmetic method using said compositions.

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Geneva, Switzerland

Olivier Sorg