Amgen Inc.

Amgen Research (Munich) Gmbh

Xencor, Inc.

Amgen Research Gmbh

Olivier Nolan-Stevaux

John R Desjarlais

Matthew J Bernett

Tobias Raum

Gregory L Moore

Rumana Rashid

Seung Yup Chu

Patrick Hoffmann

Umesh Muchhal

Ralf Lutterbüse

Neeraj Jagdish Agrawal

Claudia Blümel

Kevin Graham

Elisabeth Nahrwold

Christoph Dahlhoff

Darren L Bates

Mercedesz Balazs

Ralf Lutterbuese

Christopher Murawsky

Jennitte LeAnn Stevens

Benjamin M Alba

Agnieszka Kielczewska

Marc Panzer

Cong Li

Wibke Deisting

Lisa Winkel

Jonas Karl-Josef Honer

Wentao Chen

Claudia Bluemel

Nathan William Pierce

The present invention provides anti-CCR8 antibodies and antigen-binding fragments thereof, and methods of making and using said anti-CCR8 antibodies and antigen-binding fragments thereof.

Anti-CCR8 antibodies and uses thereof

The disclosure provides novel antigen-binding proteins that bind STEAP1 and methods of use.

Anti-STEAP1 antigen-binding protein

The present invention relates to a bispecific antibody construct comprising a first binding domain which binds to human CD70 on the surface of a target cell and a second binding domain which binds to human CD3 on the surface of a T cell. Moreover, the invention provides a polynucleotide encoding the antibody construct, a vector comprising said polynucleotide and a host cell transformed or transfected with said polynucleotide or vector. Furthermore, the invention provides a process for the production of the antibody construct of the invention, a medical use of said antibody construct and a kit comprising said antibody construct.

Antibody constructs for CD70 and CD3

Growing community of inventors

Millbrae, CA, United States of America

Olivier Nolan-Stevaux