Aptar France Sas

Olivier His

Anthony Saussaye

David Fabien

Thomas Gomez

Cyril Meziere

Vincent Hebert

Thierry Hubert

Vincent HÉBERT

An autoinjector comprising a body () that is adapted to receive a reservoir (S), said reservoir (S) containing fluid and including a piston (P) and a needle (A), such as a pre-filled syringe, said autoinjector further comprising an actuator sleeve () that is movable relative to said body () between projecting positions in which said actuator sleeve () projects out from said body () at least in part, and an actuated position in which said actuator sleeve () is moved axially into said body (), said actuator sleeve () being in a first projecting position before actuation of the autoinjector, and in a second projecting position after actuation of the autoinjector; said actuator sleeve () being urged towards said projecting positions by a spring (), said autoinjector including a removable cap () that is fastened to said body () before the autoinjector is used, said removable cap (), when it is fastened to said body (), moving said actuator sleeve () axially relative to said first projecting position through a distance (d) into said body (), against the force of said spring (), such that when said removable cap () is removed from said body (), said spring () returns said into said first projecting position.

Auto-injector

An autoinjector having a body () receiving a reservoir (S), the reservoir containing fluid and including a piston (P); a piston rod () adapted to co-operate with the piston (P) of the reservoir (S), the piston rod () movable by an injection spring () between a primed position and an injection position in which the piston rod () has moved the piston (P) of the reservoir (S); and an indicator device for indicating that the autoinjector may be removed from the injection site. The autoinjector includes a retarding system for delaying actuation of the indicator device relative to the end of injection, the retarding system including a dashpot () containing a fluid and a piston () arranged in the dashpot (). The retarding system has the dashpot (), the piston (), a retarding spring (), a locking key (), and the piston rod (), and the piston rod ().

A molding assembly for manufacturing a syringe barrel, each syringe barrel provided with a cannula and having a cylindrical portion and a hub portion to which the cannula is fastened. A mold unit is provided having a first mold portion, a second mold portion axially movable relative to the first mold portion between an open position and a closed position, and a core situated in the mold cavity; and a clip unit for the cannula movable between an open position in which a cannula can be loaded in a proximal axial end of the clip, and a closed position. The clip unit is axially movable so as to arrange a cannula in the mold cavity, the movement of the clip being independent of the axial movement of the first and second mold portions between the open and closed positions of the mold unit.

Moulding assembly and method for producing a syringe body

An auto-injector having a body () receiving a reservoir (S) and including a piston (P); a piston rod () movable between a primed position and an injection position in which the piston rod () has moved the piston (P) to inject fluid into an injection site; and a visual, audible, and/or tactile indicator device for indicating that the autoinjector may be removed from the injection site. The autoinjector includes a retarding system to delay actuating the indicator device relative to the end of injection and that includes a dashpot (), a shear member () and a fluid. The dashpot or the shear member is rotatably mounted in the body and the other is stationary in rotation, the turning of one relative to the other being braked by shearing the fluid contained in the dashpot. The dashpot and shear member include projections that impede the flow of the fluid.

Auto-injector with a system for delaying the device indicating the removal of the auto-injector

An autoinjector having a body () receiving a reservoir (S) containing fluid and a piston (P); a piston rod () movable by an injection spring () between a primed position and an injection position; and a visual, audible, and/or tactile indicator for indicating the autoinjector may be removed from the injection site. The autoinjector including a retarding system for delaying actuation of the indicator relative to the end of injection, and including a dashpot () containing a fluid, a piston () in the dashpot, the dashpot or the piston movable in the body during actuation of the retarding system with the other stationary relative to the body, resulting in the fluid moving out from the dashpot through a flow passage () to brake movement.

Auto-injector with a delay system

An autoinjector having a body () receiving a reservoir (S), the reservoir containing fluid and including a piston (P), such as a pre-filled syringe, and stationary in said body (); a piston rod () that co-operates with the piston (P), the piston rod () movable between a primed position and an injection position in which the piston rod has moved the piston so as to inject the fluid into an injection site; and a visual, audible, and/or tactile indicator device for indicating to the user that the autoinjector may be removed from the injection site, the indicator device arranged at the rear end of the body (), remote from the injection site. The autoinjector includes a retarding device to delay actuating the indicator device relative to the end of injection, the retarding device having an epicyclic gear train having at least one stage, and advantageously two stages.

Auto-injector with a delay device comprising an epicyclic gear train

An autoinjector having a body to receive a reservoir and an actuator sleeve including a contact end and extending inside the body and movable relative to the body between projecting positions and an actuated position. The actuator sleeve is in a first projecting position before actuation of the autoinjector and in a second projecting position after actuation. The actuator sleeve, in the second projecting position, extends axially further out from the body than in the first projecting position and includes an annular zone that, in the first projecting position, is arranged inside the body and in the second projecting position is arranged outside the body. The annular zone includes a visual indicator that the autoinjector has been actuated. Axially adjacent the annular zone the actuator sleeve includes a shoulder, projecting radially outwards relative to the visual indicator, thereby protecting the indicator against contact with the inside of the body.

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Saint Etienne du Vauvray, France

Olivier His