Firmenich Sa

Olivier Haefliger

Xiu-Feng He

Pan Li

Qi Rong Wang

Dan-Ting Yin

Wen-Juan Xiang

Jian Li

Michel Schalk

Qi Wang

Yu-Hua Zhang

Laurent Daviet

Fabienne Deguerry

Eric Wen-Bo Liu

Zong-Xia Yu

Provided herein is a method of improving the taste profile of a glucosylated terpene glycoside (GTG).

Glucosylated terpene glycosides

The present application relates to a method of producing drimenol and/or drimenol derivatives by comprising contacting at least one polypeptide with farnesyl diphosphate (FPP). The method may be performed in vitro or in vivo. Also provided are amino acid sequences of polypeptides useful in the methods and nucleic acids encoding the polypeptides described. The method further provides host cells or organisms genetically modified to express the polypeptides and useful to produce drimenol and/or derivatives of drimenol.

Sesquiterpene synthases for production of drimenol and mixtures thereof

Provided herein is a method of improving the taste profile of a glucosylated terpene glycoside (GTG) comprising:

Described herein is a method of producing drimenol and/or drimenol derivatives, the method including contacting at least one polypeptide with farnesyl diphosphate (FPP). The method may be performed in vitro or in vivo. Also described herein are amino acid sequences of polypeptides useful in the methods and nucleic acids encoding the polypeptides described. Also described herein are host cells or organisms genetically modified to express the polypeptides and useful to produce drimenol and/or derivatives of drimenol.

The present invention discloses a method of producing drimenol and/or drimenol derivatives by contacting a polypeptide with farnesyl pyrophosphate. Also provided is an amino acid sequence of a polypeptide useful in the methods of the invention and nucleic acid encoding the polypeptides of the invention. The method further provides host cells or organisms genetically modified to express the polypeptides of the invention and useful to produce drimenol and/or drimenol derivatives.

Drimenol synthases III

The present invention relates to a method of producing drimenol and/or drimenol derivatives by contacting at least one polypeptide with farnesyl diphosphate. The method may be performed in vitro or in vivo. The present invention also provides amino acid sequences of polypeptides useful in the method of the invention and nucleic acid encoding the polypeptides of the invention. The method further provides host cells or organisms genetically modified to express the polypeptides of the invention and useful to produce drimenol and/or drimenol derivatives.

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Geneva, Switzerland

Olivier Haefliger