Aventis Animal Nutrition S.a.

Rhone-poulenc Fibres Et Polymeres S.a.

Rhone-poulenc Chimie

Rhone-poulenc Agro

Olivier Favre-Bulle

Catherine Jourdat

Dominique Petre

Jerome Pierrard

Jean-Marc Ricca

Denis Thibaut

Georges Gros

Dominique Horbez

Jo&euml;l Crouzet

Philippe Morel

Didier Faucher

Joel Crouzet

Marie-Claude Bontoux

Herv&eacute; Ponceblanc

Jérôme Pierrard

Anne-Marie Le Coq

Christophe David

Carole Guitton

The invention concerns a modified nitrilase with modulated selectivity, characterized in that it comprises in position 162 an amino acid residue different from the original amino acid residue.

Method for modulating nitrilase selectivity, nitrilases obtained by said method and use thereof

The invention concerns a method for preparing &agr;-phenylalanine ester with substantially enantiomeric purity of formulae (I) and (II) wherein Alk represents a linear or branched C -C alkyl radical, characterized in that it consists in contacting a mixture of &agr;-phenylalanine ester enantiomers with a lipase, a protease or an esterase.

Enzymatic method for preparing synthesis intermediates

The invention concerns a method for preparing methionine aminoamide. The invention also concerns the preparation of methionine without co-production of salts, from an aqueous solution containing essentially methionine aminonitrile by producing during a first step aminoamide followed by two complementary steps.

Process for preparing methionine

The present invention relates to an enzyme with amidase activity, particularly towards substrates of the oligomer type derived from PA 6.6 (formula I) and/or PA 6 (formula II), said enzyme being characterized by a ratio

Enzymes and microorganisms having amidase activity for hydrolysing polyamides

The present invention relates to a process for the enzymatic hydrolysis of polyamides 6.6 to give adipic acid monomers and hexamethylenediamine monomers. The present invention further relates to an enzyme with amidase activity particularly towards substrates of the oligomer type derived from PA 6.6 and/or PA 6, said enzyme being characterized in that it consists of a peptide sequence corresponding to SEQ ID NO: 1 in the attached sequence listing and/or at least one polypeptide homologous to this sequence. The invention further relates to the DNA coding for said enzyme and to the biological precursors thereof The invention further relates to the microorganisms capable of producing this enzyme and to the hydrolysis process in which this enzyme and/or these microorganisms are applied.

Enzymes and micro organisms with amidase activity which hydrolyze polyamides

Industrial scale process for the preparation of 2-hydroxy-4-methylbutyric acid using a nitrilase

Contaminating trace amounts of byproduct dihalocarboxylic acids or salts thereof are removed from aqueous solutions which comprise less than 1,000 ppm of same and at least 20% by weight of amino acids or amino acid derivatives, to render such aqueous solutions nonirritating to biological membranes and suitable for cosmeticology applications, by directly contacting the original aqueous solutions with either (a) about 1 to 100 ppm of a microorganism producing an enzyme specific for the decomposition of said dihalocarboxylic acids or salts thereof, or (b) about 0.1 to 10 ppm of such enzyme, per se.

Biological removal of dihalocarboxylic acid irritants

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Lyons, France

Olivier Favre-Bulle