Ludwig Institute for Cancer Research Limited

Olivier DeBacker

Thierry R Boon-Falleur

Benoit Van Den Eynde

Pierre Van Der Bruggen

The invention relates to nucleic acid molecules which encode members of the GAGE family of tumor rejection antigen precursors and their use.

Isolated nucleic acid molecules which encode GAGE genes and uses thereof

A new family of tumor rejection antigen precursors, and the nucleic acid molecules which code for them, are disclosed. These tumor rejection antigen precursors are referred to as GAGE tumor rejection antigen precursors, and the nucleic acid molecules which code for them are referred to as GAGE coding molecules. Various diagnostic and therapeutic uses of the coding sequences and the tumor rejection antigens, and their precursor molecules are described. Tumor rejection antigens are also shown.

Isolated, truncated nucleic acid molecules which code for gage tumor

Isolated, nucleic acid molecules which code for gage tumor rejection

Isolated peptides derived from the gage tumor rejection antigen

Isolated peptides derived from tumor rejection antigens, and their use

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Brussels, Belgium

Olivier DeBacker