Palo Alto Research Center Inc.

Siemens Healthcare Gmbh

Siemens Aktiengesellschaft

Carl Zeiss Ag

Siemens Healthcare Diagnostics Gmbh

Oliver Schmidt

Peter Kiesel

Michael Bassler

Noble Marshall Johnson

Sandro Francesco Tedde

Andreas Kanitz

Patrick Yasuo Maeda

Meng H Lean

Oliver Hayden

Uma Srinivasan

Oliver Wolst

Richard H Bruce

Armin Rainer Völkel

Christian G Van De Walle

Bernd Spruck

David Hartmann

Lukas Richter

Rene Fischer

Christian Koos

Patric Buechele

Ali Kamen

Armin R Volkel

Michael A Kneissl

Thomas Engel

Huangpin Ben Hsieh

Manfred Stanzel

Enrico Geissler

Noha Youssry El-Zehiry

Marcus Radicke

Stefan Richter

Frank Hoeller

Cristina Alvarez Diez

Manfred Rührig

Frank Höller

H Ben Hsieh

Gaby Marquardt

Lars-Christian Wittig

Matthias Ugele

Rainer Gransee

Manfred Ruehrig

Daniela Seidel

Simon Brattke

Peter Michael Dueppenbecker

Kiesel Peter

Setu Mohta

Arnd Willy Walter Geis

Vishnu Vatheriparambil Mohandas

Oliver H Wolst

A filter system is for the local attenuation of X-radiation. In an embodiment, the filter system includes a filter device, arranged in a beam path of an X-ray apparatus and including a channel arrangement, the channel arrangement including a multiplicity of channel sections extending in parallel on a plane; a supply device to provide a 2-phase fluid flow containing drops of an absorber liquid, to absorb X-radiation and a carrier liquid transparent to X-radiation; and a sorting section, including an input connected to the supply device, a first output connected to the channel arrangement, a second output, and a deflection device to direct individual drops of the absorber liquid to the first output or the second output.

Filter system for the local attenuation of X-radiation, X-ray apparatus and method for locally changing the intensity of X-radiation

An optical microscopy device for detecting cellular components of a sample, includes: a light source apparatus for emitting a light beam; a specimen carrier, which can be positioned in the beam path of the light beam, for receiving the sample; an objective lens which is provided downstream of the specimen carrier in the beam path of the light beam; and a camera chip which has pixels of a predefined pixel size, the camera chip being designed to detect the light beam after it passes through the objective lens and being designed to generate a camera image, a field number in the intermediate image downstream of the objective lens being greater than 25 millimeters.

Microscopy device

A mammography installation includes a first compression device; a second compression device including an integrated X-ray detector; an X-ray emitter; a support device, arranged at the first compression device or at the second compression device, and including an integrated ultrasound transducer, the support device and the integrated ultrasound transducer being designed to be deformable so as to be adaptable to the breast of a patient, the integrated ultrasound transducer being arranged on an elastic substrate; and a breast locating region, provided between the support device and the first compression device or the second compression device that is situated opposite the first compression device or the second compression device at which the support device is arranged. The breast of the patient is positionable in the breast locating region. Further, the integrated ultrasound transducer is oriented in a direction of the breast locating region.

Mammography imaging

The present invention relates to an improved method for marker-free detection of a cell type of at least one cell in a medium using microfluidics and digital holographic microscopy, as well as a device, particular for carrying out the method.

High accuracy 5-part differential with digital holographic microscopy and untouched leukocytes from peripheral blood

An in vitro method for the marker-free determination of a cell type of a cell in a biological sample is disclosed, a microscopic device being configured to detect a height profile of the cell with respect to a carrier plate. An embodiment of the method performed by a cell analysis device, include: determining a cell compartment of the cell on the basis of the detected height profile, determining a predetermined quantitative cell feature on the basis of the determined cell compartment, and determining the cell type of the cell on the basis of the determined quantitative cell feature. A correspondingly designed cell analysis device and a corresponding microscopic device are also disclosed.

In vitro method for the label-free determination of a cell type of a cell

An embodiment relates to a composition including at least two powders. The powders are selected from the group including a powder including a p-doped perovskite; a powder including an n-doped perovskite; and a powder including an undoped perovskite. A method for producing the composition, a method for producing a detector using the composition, and a detector, in particular an X-ray detector, produced thereby are also disclosed.

Perovskite particles for producing X-ray detectors by means of deposition from the dry phase

The present disclosure relates to coated particles. The teachings thereof may be embodied in coated particles, a method for their production, and the use of the coated particles in X-ray detectors, gamma detectors, UV detectors, or solar cells. For example, some embodiments include particles comprising: perovskite crystals of the type ABXor ABX; wherein A comprises at least one monovalent, divalent, or trivalent element from the fourth or a higher period in the periodic table or mixtures thereof; B comprises a monovalent cation, the volumetric parameter of which is sufficient, with the respective element A, for perovskite lattice formation; and X is selected from the group consisting of halides and pseudohalides, and mixtures thereof; and a coating of at least one semiconductor material surrounding a nucleus comprising the perovskite crystals.

Coating made of a semiconductor material

The present disclosure relates to a detection layer on a substrate. For example, a detection layer may include perovskite crystals of the type ABXand/or ABX. A may include at least one monovalent, divalent or trivalent element from the fourth or a higher period in the periodic table and/or mixtures thereof. B may include a monovalent cation, the volumetric parameter of which is sufficient, with the respective element A, for perovskite lattice formation. X may be selected from the group consisting of anions of halides and pseudohalides. The layer may have a thickness of at least 10 &#x3bc;m.

Detection layer comprising perovskite crystals

A coated scintillator particle, a scintillator particle coated with a semiconducting photoactive material, a method for producing such scintillator particles, an x-ray detector, a gamma-ray detector, and a UV detector using such coated scintillator particles, a method for producing such x-ray detector, gamma-ray detector, or UV detector, and the use of the coated scintillator particles for detecting high-energy radiation, e.g., radiation, gamma radiation and/or x-rays, are disclosed.

Scintillators comprising an organic photodetection shell

A detector for high-energy radiation, e.g., for x-radiation and/or UV radiation, may include (a) a substrate having a first electrical contact, (b) optionally a first intermediate layer, (c) a layer including an organic matrix of a photoactive material and insoluble scintillator particles distributed substantially homogeneously in the organic matrix, (d) optionally a second intermediate layer, and (e) a second electrical contact, wherein the mixture ratio between the scintillator particles and the organic matrix in layer (c) is selected in such a way that the intermediate space filled with the organic matrix has a distance between two scintillator particles that corresponds to at most five times the depth of penetration of the emitted radiation of the scintillator particles. A method for producing a corresponding detector is also disclosed.

Hybrid-organic X-ray detector with conductive channels

A method and system for using spatially modulated excitation/emission and relative movement between a particle (cell, molecule, aerosol, . . . ) and an excitation/emission pattern are provided. In at least one form, an interference pattern of the excitation light with submicron periodicity perpendicular to the particle flow is used. As the particle moves along the pattern, emission is modulated according to the speed of the particle and the periodicity of the stripe pattern. A single detector, which records the emission over a couple of stripes, can be used. The signal is recorded with a fast detector read-out in order to capture the 'blinking' of the particles while they are moving through the excitation pattern. This concept enables light detection with high signal-to-noise ratio and high spatial resolution without the need of expensive and bulky optics.

Method and system implementing spatially modulated excitation or emission for particle characterization with enhanced sensitivity

A measuring unit is set up to determine a relative position and relative orientation between the measuring unit and an arrangement of at least three optical elements. The measuring unit comprises a length measuring device, which emits measuring beams at at least three locations spaced apart from one another, and at least one beam directing device set up to direct the measuring beams to optical elements of the arrangement. The beam directing device is controllable in order to guide at least one of the measuring beams to a plurality of optical elements of the arrangement in a time-sequential manner in order to carry out a plurality of length measuring operations in a time-sequential manner in such a manner that, in the plurality of length measuring operations, each measuring beam of the at least one measuring beam strikes precisely one of the optical elements. A total of six lengths are measured in this manner.

Measuring unit, measuring system and method for determining a relative position and relative orientation

An arrangement for modifying the local intensity of x-ray radiation includes an x-ray filter with a plurality of absorption chambers, which may be filled by a ferrofluid. The absorption chambers are stacked in the x-ray beam direction. The x-ray filter includes a plurality of storage containers in which the ferrofluid may be stored. Each of the absorption chambers is connected to a respective one of the storage containers. The absorption of the x-ray radiation is achieved as a result of individual absorption chambers being filled with the ferrofluid. By filling a different number of absorption chambers, the local intensity of the x-ray radiation may be modified easily, precisely and quickly.

Arrangement and method for modifying the local intensity of x-ray radiation

A method is provided for extracting the position of a particle, e.g., a moving or stationary particle that is excited or is emitting light. The method includes, among other steps, detecting and recording a signal based on, for example, the movement of the particle, a correlation step to eliminate noise and to create a transformed signal, a matching or fitting step to match the transformed signal to a fit function and an extracting or determining step to determine the position of the particle from the fit function. In one form, at least two particle positions are detected so that the distance between the subject particles can be determined.

Method and system for evaluation of signals received from spatially modulated excitation and emission to accurately determine particle positions and distances

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Palo Alto, CA, United States of America

Oliver Schmidt