Danisco US Inc.

Bayer Pharma Aktiengesellschaft

Danisco A/s

Direvo Industrial Biotechnology Gmbh

Basf Se Corporation

Dupont Nutrition Biosciences Aps

Danisco US Inc., Genencor Division

Oliver Kensch

Birgitta Leuthner

Ulrich Kettling

Michael C Ward

Michael D Ward

Andrei Miasnikov

Vijay Kumar

Andre Koltermann

Jayarama K Shetty

Hans-Georg Lerchen

Nils Griebenow

Anne-Sophie Rebstock

Beatrix Stelte-Ludwig

Yolanda Cancho Grande

Michael Jay Pepsin

Simone Greven

Jan Tebbe

Christoph Mahlert

Anette Sommer

Marguerite A Cervin

Ulrich Haupts

Klaus Pellangahr

Mai Faurschou Isaksen

Nadine Koch

Klaus Pellengahr

Steven Sungin Kim

Steve Sungjin Kim

Klaus Schulze Pellengahr

Andreas Scheidig

Soeren Dalsgaard

Wayne M Coco

Ute Beister

Markus Rarbach

Klaus Schulze-Pellengahr

Søren Dalsgaard

Ute Solloch

Steve Kim

Soren Dalsgaard

The invention relates to site specific homogeneous binder drug conjugates of kinesin spindle protein inhibitors, to active metabolites of these conjugates, to processes for preparing these conjugates, to the use of these conjugates for the treatment and/or prophylaxis of diseases and to the use of these conjugates for preparing medicaments for treatment and/or prevention of diseases, in particular hyperproliferative and/or angiogenic disorders such as, for example, cancer diseases. Such treatments can be carried out as monotherapy or else in combination with other medicaments or further therapeutic measures.

Site specific homogeneous with KSP inhibitors

Provided herein are variants ofsp. phytases that may be used in industrial applications including methods for starch liquefaction, alcohol fermentations and for enhancing phosphate digestion in foods and animal feeds.

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The present invention relates to enzymes and processes. In particular, there is described an isolated polypeptide comprising the amino acid sequence corresponding tophytase or a homologue, a modified form, a functional equivalent or an effective fragment thereof. There is also described a host cell transformed or transfected with a nucleic acid encoding a bacterial phytase enzyme or a modified form as well as the use of such a phytase or modified form in food or animal feed.

Mutant citrobacter freundii phytase polypeptide

The present disclosure provides novel mannanase variants which have an amino acid sequence that varies from that of the parent/wild typemannanase, and which have one or more advantageous properties like improved thermo stability; temperature/activity profile; pH/activity profile; specific activity; and pH/protease-sensitivity. The novel mannanase variants are useful and used in alcohol fermentations processes and/or productions, for coffee extraction and the processing of coffee waste, as a supplement to food and feed, for enzyme aided bleaching of paper pulps, as bleaching and/or desizing agent in textile industry, for oil and gas well stimulation by hydraulic fracturing, as detergent, as baking ingredients, for removal of biofilms and in delivery systems, for grain processing or for the processing of renewable resources intended for the production of biological fuels, and in the textile, oil drilling, cleaning, laundering, detergent, and cellulose fiber processing industries.

Mannanase variants

Provided herein are improved variants of polypeptides having cellobiohydrolase II activity, nucleic acids encoding the polypeptides, vectors, host cells containing the nucleic acids and methods for producing the polypeptides. The polypeptides encompassed by this disclosure may be used in numerous applications including the use of the polypeptides for the production of biofuels and for the synthesis of platform chemicals or biopolymers from renewable sources.

Polypeptides having cellobiohydrolase II activity

The present invention relates to variant phytase enzymes having altered properties.

The present invention relates to enzymes and processes. In particular, there is described a host cell transformed or transfected with a nucleic acid encoding a bacterial phytase enzyme and variants thereof.

Enzymes

The present invention provides an insertion, deletion and/or substitution mutein of wild-type&#x3b2;-mannanase having enhanced thermostability, proteolytic stability, specific activity and/or stability at low pH, a nucleic acid molecule encoding said mannanase mutein, a composition comprising said mannanase mutein; a method for its preparation, and its use for food and feed processing, for coffee extraction and the processing of coffee waste, as a supplement to food and feed, for enzyme aided bleaching of paper pulps, as bleaching and/or desizing agent in textile industry, for oil and gas well stimulation by hydraulic fracturing, as detergent, for removal of biofilms and in delivery systems, or for the processing of renewable resources intended for the production of biological fuels.

Mannanases

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Cologne, Germany

Oliver Kensch