Illumina Cambridge Limited

Illumina Corporation

Oliver Jon Miller

Bradley Kent Drews

Mark J Nibbe

James Christopher Blake

Gudrun Stengel

Daniel Leonard Fuller

Michael Steven Becker

Mohammed Kafeel Ahamed

Tarun Kumar Khurana

Paul Crivelli

Darren Segale

Michael Thomas Dangelo

Gary J Watts

Wesley A Cox-Muranami

Jennifer Olivia Foley

Jonathan Mark Boutell

Grace DeSantis

Junhua Zhao

Andrew Slatter

Jian-Sen Li

Stephen M Gross

Hayley Marianne Hogan

Michael Dangelo

Darren Robert Segale

Gary Watts

Wesley Cox-Muranami

Daniel L Fuller

This disclosure describes a hybridization buffer including a crowding agent, a method that includes using the hybridization buffer, and a kit including the hybridization buffer. This disclosure also describes blockers for use in hybrid capture methods, methods of using those blockers, and a kit including those blockers. Additionally, this disclosure describes a method of hybrid capture that does not include amplifying the library members using PCR prior to sequencing the library members.

Compositions and methods for improving library enrichment

The assembly includes a docking console and a manifold. The docking console includes a cartridge support surface having a first end and a second end. The manifold has one or more wells defined therein. The docking console further includes a manifold retention bracket to releasably hold the manifold against a fluid cartridge supported on the cartridge support surface at an interface position such that the one or more wells are in fluid communication with the fluid cartridge and a biased seal bar to press the fluid cartridge against the manifold held by the manifold retention bracket. A hydrophilic porous frit disposed within at least one of the wells and is to permit liquid to flow through the outlet aperture but prevent gas from passing through the outlet aperture.

Liquid sample loading

The present disclosure is concerned with compositions and methods for reducing the steps used in the generation of monoclonal clusters by combining the enzymes used for linearization and removal of unused surface primers.

Methods and compositions for cluster generation by bridge amplification

An apparatus for directing fluid into and out of a fluidic device includes two or more fluid prime channels connected to a fluid inlet of the fluidic device, a flow control valve for each fluid prime channel to control flow between the fluid prime channel and the fluid inlet, one or more outlet channels connected to a fluid outlet of the fluidic device, and a flow control valve for each outlet channel to control flow between the fluid outlet and the associated outlet channel. An apparatus for delivering fluids to a fluid inlet includes a plate that is rotatable about an axis of rotation and a plurality of fluid compartments disposed on the plate, each compartment having a fluid exit port disposed at a common radial distance from the axis of rotation and positioned to align with the fluid inlet as the plate rotates about the axis of rotation.

Fluid caching

Growing community of inventors

Cambridge, United Kingdom

Oliver Jon Miller