Sony Deutschland Gmbh

Sony Corporation

Sony International (europe) Gmbh

Oxford Nanopore Technologies Limited

Oliver Harnack

Akio Yasuda

Jurina Wessels

William E Ford

Eriko Matsui

Nobuyuki Matsuzawa

James Anthony Clarke

Terry Reid

Haruo Watanabe

Ingeborg Hospach

Tadashi Mizutani

Takae Yamauchi

Susumu Kitagawa

Claire Basquin

Eriko Sony Corporation Matsui

Haruo Sony Corporation Watanabe

The present invention relates to a device for processing an analyte and to a method of processing and/or detecting an analyte using said device.

Device for processing an analyte and a method of processing and/or detecting an analyte using said device

A functional molecular element exhibiting its function under the operation of an electrical field is provided. A compound is used in which a pendant molecule, formed by 4-pentyl-4'-cyanobiphenyl, exhibiting positive dielectric constant anisotropy or a dipole moment along the direction of the long axis of the molecule, is covalently bonded to an electrically conductive linear or film-shaped principal-axis molecule having a conjugated system. The pendant molecule is changed in its orientation on application of an electrical field to change the conformation to switch the electrical conductivity of the electrically conductive principal-axis molecule.

Functional molecular element and functional molecular device

A method of fabricating a membrane having a tampered pore, a polymeric membrane having a tapered pore, and uses of such polymeric membrane are disclosed. The membrane includes apertures of increasing diameter which are aligned with each other to form the tapered pore.

Method of fabricating a membrane having a tapered pore

The present invention provides an improved process for the direct and selective metallization of nucleic acids via metal nanoparticles produced in-situ in which a nucleic acid specific metal complex is reacted with a nucleic acid to produce a metal complex-nucleic acid conjugate, non-conjugated metal complex and/or non-conjugated by-products are removed, and the metal complex-nucleic acid conjugate is reacted with a reducing agent to produce a metal nanoparticle-nucleic acid composite. The metal nanoparticle-nucleic acid composites may be used, e. g., in the formation of nanowires, for electronic networks and circuits allowing a high density arrangement.

Production of platinum particle nucleic acid composite comprising subnanometer size particles

A method of fabricating a membrane having a tapered pore, a polymeric membrane having a tapered pore, and uses of such polymeric membrane are disclosed. The membrane includes apertures of increasing diameter which are aligned with each other to form the tapered pore.

A functional molecular element is provided. The functional molecular element is adapted to change, by application of electric field, conformation of a disc shape like organic metallic complex molecule () which forms a columnar arrangement structure to exhibit function, wherein the structure of the organic metallic complex molecule is changed by application of electric field so that anisotropy of dielectric constant is changed. Accordingly, conductivity between measurement electrodes can be switched. As its stable value, there are three kinds of stable values or more. Thus, elements or devices to which such multi-value memory characteristic is applied can be constituted.

Functional molecular element

The present invention is related to a method of attaching hydrophilic species to hydrophilic macromolecules and immobilizing the hydrophilic macromolecules on a hydrophobic surface, to a nano-assembly and to uses of the nano-assembly.

Method of attaching hydrophilic species to hydrophilic macromolecules and immobilizing the hydrophilic macromolecules on a hydrophobic surface

A functional molecular device displaying its functions under the action of an electrical field is provided. A Louis base molecule, exhibiting positive dielectric constant anisotropy or exhibiting dipole moment along the long-axis direction of the Louis base molecule, is arrayed in the form of a pendant on an electrically conductive linear or film-shaped principal-axis molecule of a conjugated system, via a metal ion capable of acting as a Louis acid. The resulting structure is changed in conformation on application of an electrical field to exhibit its function. The electrically conductive linear or film-shaped principal-axis molecule and the Louis base molecule form a complex with the metal ion. On application of the electrical field, the Louis base molecule performs a swinging movement or a seesaw movement to switch the electrical conductivity of the principal-axis molecule. This molecule exhibits electrical characteristics which may be reversed depending on whether or not the molecule has been subjected to electrical field processing. A molecular device having a function equivalent to one of CMOS may be produced from one and the same material.

Functional molecular device

A functional molecular element whose functions can be controlled by an electric field based on a new principle. A Lewis base molecule () with positive permittivity anisotropy or a dipole moment in the major axis direction of the molecule is disposed, via a metal ion () that can act as a Lewis acid, in a pendant-like form on a key molecule () in the form of a line or film that has a conjugated system and exhibits conductivity, thereby forming a functional molecular elementthat can realize a function where the conformation changes due to the application of an electric field. The conductive key molecule () and the Lewis base molecule () form a complex with the metal ion (). When an electric field is applied in a direction perpendicular to the plane of the paper in FIG.(), for example, the Lewis base molecule () performs a 90&#xb0; 'neck twisting' movement with the up-down direction in the drawing as the axis. Also, when an electric field is applied in the up-down direction in the drawing as shown in FIG.(), the Lewis base molecule () performs a 'see-saw' movement with the direction perpendicular to the plane of the paper as the axis, thereby switching the conductivity of the conductive key molecule ().

The invention relates to a method for defect and conductivity engineering of an individual part in a conducting nanoscaled structure by generating heat-induced migration, melting, sputtering and/or evaporation of conductive material of the nanoscaled structure by directing a focussed electron beam on this individual part of the structure to be engineered. The invention further relates to the use of a secondary electron microscope having a filter for detecting back scattered electrons for such a method and a respective secondary electron microscope having such a filter for detecting back scattered electrons.

Method for defect and conductivity engineering of a conducting nanoscaled structure

The invention relates to a process for the metallization of nucleic acids, comprising providing tris(hydroxymethyl)phosphine-Au (THP-Au) particles or derivatives thereof, binding said THP-Au particles to a nucleic acid to produce a metal nanoparticle-nucleic acid composite, and treatment of the metal nanoparticle-nucleic acid composite with an electroless plating solution. The invention further relates to a metallized nucleic acid obtainable according to such a method and a nanowire including a method for the manufacture of a nanowire.

Metallization of nucleic acids via metal nanoparticles produced ex-situ

The present invention relates to a process for immobilization of nucleic acid molecules on a substrate, wherein the substrate is treated with atomic oxygen plasma prior to immobilizing the nucleic acid molecules thereon. The invention is further related to immobilized nucleic acid molecules and uses thereof.

Growing community of inventors

Stuttgart, Germany

Oliver Harnack