Cognis IP Management Gmbh

Cognis France S.a.s.

Olga Freis

Philippe Moussou

Louis Danoux

Laurent Bailly

Jean-Luc Contet-Audonneau

Véronique Gillon

Philippe Grisoni

Gilles Pauly

Philippe Moser

Andreas Rathjens

Cosmetic compositions comprising calcium citrate and at least one N-acylated aminoalcohol according to formula (I).  Provided is a method of treating aged skin, comprising topically applying to the aged skin a composition comprising a compound of Formula (I) in an amount effective to provide an anti-ageing effect. The compound of Formula (I) is used to prevent skin and/or to help to maintain or improve moisture retention and/or to fight against the signs of skin ageing. The N-acylated aminoalcohol of formula (I) acts as a ceramidase inhibitor. The combination of at least one compound of formula (I) and calcium citrate stimulates keratinocyte differentiation.

Cosmetic composition containing calcium citrate and N-acylated aminoalcohol derivative

Cosmetic composition containing calcium citrate and N-acylated aminoalcohol derivative to prevent dry skin and signs of cutaneous ageing

Oligopeptides according to formula (I) and/or (II), R-Tyr-Pro-Trp-Phe-NH(I, SEQ ID NO:1); R-Tyr-Pro-PhePhe-NH(II, SEQ ID NO:2), wherein Ris linked to the NH-group of the amino-terminal part of Tyr and is selected from the group consisting of &#x2014;H; a linear saturated or unsaturated or branched saturated or unsaturated acyl group having 1 to 24 carbon atoms, which may be functionalized by a &#x2014;OH, &#x2014;SH, &#x2014;COOH or &#x2014;CONH+ group; a sterol or a sphingolipid group which is linked to the amino terminal part of Tyr via a bifunctional linker are disclosed. Cosmetic compositions containing the oligopeptides are also disclosed.

Oligopeptides and cosmetic compositions containing the oligopeptides

The present invention relates to substances which can be used as cosmetic ingredients, especially for skin whitening and as cosmetic agents against signs of ageing skin. The present invention also relates to the use of such substances for the manufacture of a medicament for the treatment of disorders related to the pigmentation of the skin.

Use of derivatives of 4-hydroxyphenoxy acetic acid

Oligopeptides according to formula (I) and/or (II), R-Tyr-Pro-Trp-Phe-NH(I); R-Tyr-Pro-Phe-Phe-NH(II), wherein Ris linked to the NH-group of the amino-terminal part of Tyr and is selected from the group consisting of &#x2014;H; a linear saturated or unsaturated or branched saturated or unsaturated acyl group having 1 to 24 carbon atoms, which may be functionalized by a &#x2014;OH, &#x2014;SH, &#x2014;COOH or &#x2014;CONHgroup; a sterol or a sphingolipid group which is linked to the amino terminal part of Tyr via a bifunctional linker are disclosed. Cosmetic compositions containing the oligopeptides are also disclosed.

Oligopeptides and compositions containing the oligopeptides

A composition including (a) an extract from a plant of the Asclepiadaceae family; and (b) at least one auxiliary and/or additive, and methods for treating hair growth including administering to a mammal a composition comprising an effective amount of an extract from a plant of the Asclepiadaceae family are provided.

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Seichamps, France

Olga Freis