Howmedica Osteonics Corporation

Otismed Corporation

Geometrix, Inc.

Align Technology, Inc.

Oleg Mishin

Ilwhan Park

Elena I Pavlovskaia

Boris E Shpungin

Keun Song

Michael Santarella

Venkata Surya Sarva

Irene Min Choi

Roman Waupotitsch

Charlie W Chi

Francesco Callari

Srinivas Kaza

Sergey Nikolskiy

Arthur L Zwern

Mikhail Tsoupko-Sitnikov

Sandor Fejes

Esfandiar Bandari

Gérard G Medioni

David Guigonis

Jinlong Chen

Anrong Peng

Olga Sominskaya

Vladimir Shamgin

A computer-implemented method of preoperatively planning a surgical procedure on a knee of a patient including determining femoral condyle vectors and tibial plateau vectors based on image data of the knee, the femoral condyle vectors and the tibial plateau vectors corresponding to motion vectors of the femoral condyles and the tibial plateau as they move relative to each other. The method may also include modifying a bone model representative of at least one of the femur and the tibia into a modified bone model based on the femoral condyle vectors and the tibial plateau vectors. And the method may further include determining coordinate locations for a resection of the modified bone model.

System and method for image segmentation, bone model generation and modification, and surgical planning

A method for planning an arthroplasty procedure on a patient bone. The method may include accessing generic bone data stored in a memory of a computer, using the computer to generate modified bone data by modifying the generic bone data according to medical imaging data of the patient bone, using the computer to derive a location of non-bone tissue data relative to the modified bone data, and superimposing implant data and the modified bone data in defining a resection of an arthroplasty target region of the patient bone.

Systems and methods for surgical planning of arthroplasty procedures

Methods of manufacturing a custom arthroplasty resection guide or jig are disclosed herein. For example, one method may include: generating MRI knee coil two dimensional images, wherein the knee coil images include a knee region of a patient; generating MRI body coil two dimensional images, wherein the body cod images include a hip region of the patient, the knee region of the patient and an ankle region of the patient; in the knee coil images, identifying first locations of knee landmarks; in the body coil images, identifying second locations of the knee landmarks; run a transformation with the first and second locations, causing the knee coil images and body coil images to generally correspond with each other with respect to location and orientation.

Preoperatively planning an arthroplasty procedure and generating a corresponding patient specific arthroplasty resection guide

A method of planning an arthroplasty procedure on a femur and tibia of a patient. The method includes receiving a first two-dimensional image of the femur and the tibia, and identifying, in the first two-dimensional image, a proximal femur feature, a distal tibia feature, and a bone contour. The method further includes running a transformation process to align a bone model representative of the femur and the tibia into a coordinate system with the first two-dimensional image, the bone model having a bone model contour that is aligned with the bone contour of the femur and the tibia in the first two-dimensional image. And the method further includes applying an implant model to the bone model in order to determine coordinate locations for the arthroplasty resection.

A smooth mating surface model defining a mating surface of a customized arthroplasty jig is generated. For example, sagittal slices of a volumetric image of a patient bone are segmented with segmentation splines. An anatomically accurate model of the patient bone is generated from the segmentation splines. The anatomically accurate model includes anatomically accurate segmentation splines. The anatomically accurate segmentation splines are transformed into mating surface contours. Any inadequate segments of the mating surface contours are modified to obtain modified mating surface contours. A mating surface model of the patient bone is generated based on the mating surface contours and the modified mating surface contours. Three-dimensional cross-sections of the mating surface model are smoothed to generate the smooth mating surface model.

Generation of a mating surface model for patient specific cutting guide based on anatomical model segmentation

A custom arthroplasty guide and a method of manufacturing such a guide are disclosed herein. The method of manufacturing the custom arthroplasty guide includes: a) generating medical imaging slices of the portion of the patient bone; b) identifying landmarks on bone boundaries in the medical imaging slices; c) providing model data including image data associated with a bone other than the patient bone; d) adjusting the model data to match the landmarks; e) using the adjusted model data to generate a three dimensional computer model of the portion of the patient bone; f) using the three dimensional computer model to generate design data associated with the custom arthroplasty guide; and g) using the design data in manufacturing the custom arthroplasty guide.

System and method for image segmentation in generating computer models of a joint to undergo arthroplasty

Methods of manufacturing a custom arthroplasty resection guide or jig are disclosed herein. For example, one method may include: generating MRI knee coil two dimensional images, wherein the knee coil images include a knee region of a patient; generating MRI body coil two dimensional images, wherein the body coil images include a hip region of the patient, the knee region of the patient and an ankle region of the patient; in the knee coil images, identifying first locations of knee landmarks; in the body coil images, identifying second locations of the knee landmarks; run a transformation with the first and second locations, causing the knee coil images and body coil images to generally correspond with each other with respect to location and orientation.

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Foster City, CA, United States of America

Oleg Mishin