Slagteriernes Forskningsinstitut

A/s N. Foss Electric

Allergifonden Af 1981

A/s Lundbeck Export Division Ltd.

Ole-Christian Bjarno

Per S Skov

Steen R Christoffersen

A histamine diagnostic assay device is provided in which glass microfibers treated with a polar organic polymer are deposited onto a carrier and used to selectively bind histamine in a sample. The polar organic polymer reduces the affinity of the glass microfibers for interfering components of the sample while substantially retaining the histamine-binding capacity. Preferably, the glass microfibers are provided as a conglomerate with the polar organic polymer. An agent which induces the release of histamine from cells in the sample may be included in the device.

Class microfiber histamine assay device

The histamine in a sample is determined by contacting the sample with a histamine binding agent, such as glass, which has been treated, e.g., with a polar organic polymer, to reduce the affinity of the agent for an interfering component of the sample while substantially retaining the agent's histamine-binding capacity. Such an agent facilitates determination of histamine in whole blood samples. Preferably, the agent is provided as a conglomerate of histamine-binding bodies, such as glass fibers, in a binder. Preferred binders are polyvinyl acetate, a vinyl acetate/ethylene copolymer, and polyvinyl alcohol or combinations thereof.

Method and means for allergy diagnosis

Process for detection of particular quality properties in individual

An antimonate, such as potassium antimonate, is used as the destruction catalyst in nitrogen determinations according to the Kjeldahl principle. Preferred catalyst comprises potassium antimonate together with potassium sulfate (for increasing the boiling point of the destruction mixture) and minor amounts of zinc sulfate and cupric sulfate (as co-catalysts).

Growing community of inventors

Holte, Denmark

Ole-Christian Bjarno