Gambro Lundia Ab

Fresenius Medical Care Deutschland Gmbh

Ztimur Ab

Ola Carlsson

Anders Wieslander

Karin Sandin

Lennart Jönsson

Gunita Forsbäck

Therese Svensson

Malin Ernebrant

Lennart Joensson

Torbjoern Linden

Torbjorn Linden

Per Kjellstrand

Simon Enarsson

Anna Bryland

Per Ulinder

Olof Jansson

Sture Hobro

Eddie Nilsson

Pascal Bernard

Husam Mohammed

Torbjörn Linden

Viktoria Hancock

Hans Peder Flank

Magnus Braide

Anna Szilagyi

Ellinor Broms

Sten-Börje Lindqvist

Tobjoern Linden

Gunita Forsback

Sten-Boerje Lindqvist

Eric Ekebacke

Tommy Wigardt

Jens Pettersson

Lennart JÖNSSON

Massimo Bormetti

The invention provides a first concentrate comprising lactate and calcium ions, said first concentrate having increased stability against precipitation at temperatures around +4° C., said first concentrate being useful for preparing a ready-to-use dialysis fluid by mixing said first concentrate with water and optionally a second concentrate comprising glucose, wherein that the lactate concentration L(expressed in moles per litre, M) of the concentrate fulfills the conditions: a) L>0.8 M; and b) L<(1.9−0.4×Ca) M; and wherein Cais the calcium concentration of the ready-to-use dialysis fluid expressed in millimoles per litre (mM).

Dialysis concentrate

A connector system () for a medical application including a male single channel fluid connector (X) designed with an outer collar (M) arranged concentric with an inner tube () and extending beyond a center collar (M), and a female single channel fluid connector (Y) is designed with an outer collar (F) arranged concentric with a tube (), wherein the male single channel fluid connector (X) is interconnectable with the female single channel fluid connector (Y) to thereby form a fluid tight single channel connection for passage of fluid, and to a luer type female single channel fluid connector (YS), and wherein the female single channel fluid connector (Y) is interconnectable with a luer type male single channel fluid connector (XS). Also a system including a plurality of the connector systems is disclosed.

Connector system with a female connector and a male connector, and a system including a plurality of the connector systems

The present invention relates to a medical solution. According to the invention the ready-for-use solution comprises phosphate in a concentration of 1.0-2.8 mM, is sterile and has a pH of 6.5-7.6. The present invention further relates to a method for producing the medical solution and the use thereof.

Dialysis solution, formulated and stored in two parts, comprising phosphate

The present invention concerns a dialysis acid precursor composition for use during preparation of a dialysis acid concentrate solution and for mixing with water, a sodium containing concentrate, and a bicarbonate containing concentrate into a ready-for-use dialysis solution. The dialysis acid precursor composition consists of powder components comprising glucose, at least one dry acid and at least one magnesium salt, and optionally potassium salt, and calcium salt. According to the invention the glucose and the at least one magnesium salt, are present as anhydrous components in the dialysis acid precursor composition.

Dialysis precursor composition product

A male fluid connector, a female fluid connector, and a connection system comprising the connectors. The connection system comprises a male connector and a female connector that both are modified such that they cannot be engaged. The connection system removes the risk of unintentional connection of the two modified connectors not intended to be connected but still allows connection of the two modified connectors to other non-modified connectors.

Male fluid connector, a female fluid connector and a fluid connection system comprising the same

The present invention concerns a dialysis acid precursor composition for use during preparation of a dialysis acid concentrate solution and for mixing with water and a bicarbonate containing concentrate into a ready-for-use dialysis solution. Said dialysis acid precursor composition consist of powder components comprising sodium chloride, at least one dry acid and at least one magnesium salt, and optionally potassium salt, calcium salt, and glucose. According to the invention said at least one magnesium salt and said optional glucose, are present as anhydrous components in said dialysis acid precursor composition.

Dialysis precursor composition

The present invention concerns a system for preparing a ready-to-use peritoneal dialysis fluid. The system comprises a) a proportioning device; b) at least one source of water; c) at least one source of first concentrate adapted for connection with a) and b), d) at least one source of second concentrate adapted for connection with a) and b), and optionally, e) at least one source of further concentrate adapted for connection with a) and b), wherein the first concentrate comprises glucose and has a pH of between 1.5 and 4, and wherein the second concentrate comprises a physiologically acceptable buffer and has a pH of between 5.5 and 9.0.

System for proportioning fluids

The present invention relates to a medical solution. According to the invention the ready-for-use solution comprises phosphate in a concentration of-mM, is sterile and has a pH of-. The present invention further relates to a method for producing the medical solution and the use thereof.

A replacement fluid for dialysis treatment includes selenium in a concentration of 0.6-1.8 &#x3bc;M, and rubidium in a concentration of 1.4-4.2 &#x3bc;M. The replacement fluid is essentially free of one or more of the trace elements selected from chromium, manganese, and copper.

Dialysis formulation

The invention relates to a dialysis formulation, optionally a citrate containing dialysis formulation, comprising selenium (Se), optionally in combination with further trace elements selected from rubidium (Rb), cobalt (Co), molybdenum (Mo), and zinc (Zn). The dialysis formulation is intended to be used in dialysis treatment.

Method for preparing a medical solution, comprising the steps of a) providing a solution comprising one or more acetylated or deacetylated amino sugar/sugars in at least one compartment of a container at a pH from 2.5 to 5.0, and b) terminal sterilization of said at least one compartment and the contents therein, is disclosed, as well as a solution used for preparing the medical solution, a container containing said solution, and use of said solution for the manufacture of a medicament for peritoneal dialysis.

Method for preparing a medical solution for the manufacture of a medicament for peritoneal dialysis

The present invention concerns a peritoneal dialysis fluid with enhanced ultrafiltration during the dialysis dwell period. According to the present invention this is achieved by a peritoneal dialysis fluid comprising sodium ions, osmotic agent and a buffer, characterised in that it comprises citrate at a level of 4 to 10 mM in a final solution ready for use.

Peritoneal dialysis fluid

The invention refers to a medical system comprising a first subsystem with a first connection portion (), and a second subsystem with a second connection portion (). The invention also refers to a device and a method for connecting the subsystems to each other. One of the subsystems contains a fluid. The connecting device is adapted to connect the subsystems to each other to permit transport of the fluid from one of the subsystems to the other subsystem. The device comprises a container () enclosing an inner space. A substantially sterile atmosphere is provided in the inner space. The container receives the first connection portion and the second connection portion in the inner space. A mechanism is provided for connecting, from outside the container, the first connection portion and the second connection portion to each other in the inner space.

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Lund, Sweden

Ola Carlsson