Seoul National University

Snu Rdb Foundation

Nibec Co., Ltd.

Ok-Jin Park

Seung Hyun Han

Chong-Pyoung Chung

Jue-Yeon Lee

Yoon Jeong Park

Ki Bum Ahn

Cheol-Heui Yun

Kee-Yeon Kum

The present invention relates to: a composition for inhibiting biofilms, containing, as an active ingredient, a peptide derived from human &#x3b2;-defensin-3; and a method for inhibiting biofilms by using the composition. The peptide according to the present invention inhibits bacterial biofilms even when used alone and exhibits a remarkably increased biofilm inhibitory effect when used in combination with a conventional dental therapeutic agent, and has an effect of preventing a tooth discoloration side effect caused by a conventional dental therapeutic agent.

Peptide for inhibiting biofilms

The present invention relates to a bone regeneration or bone formation promoting pharmaceutical composition comprising muramyl dipeptide, an analog thereof, a derivative thereof or a pharmaceutically acceptable salt thereof. In contrast to existing passive therapeutic agents which center on bone absorption suppression based on mechanisms for reducing osteoclast functionality, the composition comprising muramyl dipeptide of the present invention promotes the differentiation of osteoblasts, which are bone forming cells, and can advantageously be used in various diseases where bone formation is required as an active therapeutic agent that does not affect osteoclast.

Bone loss preventing and bone regeneration or bone formation promoting pharmaceutical composition comprising muramyl dipeptide

Growing community of inventors

Seoul, South Korea

Ok-Jin Park