Korea Institute of Science and Technology

Fasoo.com.co.ltd.

Oh-Seung Kwon

Jin Woo Park

Byung Hwa Jung

Min-Jung Kang

Yejin Lee

Euna Park

Heesoo Pyo

Woo-Seok Kwon

Yong-Ho Huh

Hafeza Akter

Junghyun Son

Won-Sang Park

Yoeseph Cho

Kyu-Gon Cho

Hana Park

Seongeun Jeon

Disclosed is a method for simultaneous analysis of neurotransmitters and/or their metabolites. The method includes (a) separating analytes including a plurality of neurotransmitters and/or their metabolites from a sample selected from body tissues, body fluids, secretions, and excretions, (b) derivatizing the analytes with ethyl chloroformate to obtain derivatives of the plurality of neurotransmitters and/or their metabolites, (c) separating the derivatives of the plurality of neurotransmitters and/or their metabolites by liquid chromatography, and (d) subjecting the separated derivatives of the neurotransmitters or their metabolites to multiple reaction monitoring (MRM) using a mass spectrometer. According to the method, a plurality of neurotransmitters in a very small amount of sample can be simultaneously analyzed in an accurate and rapid manner based on derivatization to increase the stability and ionization efficiency of the substances.

Method for simultaneous analysis of neurotransmitters and their metabolites based on derivatization

The present invention relates to a method and an apparatus for generating an index for an encrypted field in order to protect private information in database. The method for generating the index for the encrypted field according to an embodiment of the present invention constructs an index as encrypted data itself without decrypting and storing contents of the encrypted field, constructs an index using distance information between encrypted data and a pre-configured reference value when the index is constructed, calculates a distance value from the reference value even when a search is performed, and performs a search by comparing the distance value with constructed index information table. In particular, when duplicated data exists, the present invention configures the duplicated data as a set of lower leaf nodes for a leaf node, thereby minimizing a search time.

Method and apparatus for generating index for encrypted field in database

A device and a method for encoding a data column are disclosed. A schema inquiry unit inquires into a schema of an original table which is a data table for performing encoding in a database in which a plurality of data tables are stored. A backup performing unit generates schema information of a backup table on the basis of the schema of the original table, generates a backup table by using the schema information of the backup table so as to copy data of the original table into the backup table, changes the original table by adding a backup column to the original table, and inactivates constraint conditions included in the changed original table so as to copy original columns included in the changed original table into the backup column. An encoding unit encodes data of an encoding target column, a column in which encoding is to be performed in the changed original table, and enters the data in each field of the original columns of the changed original table. Then, when the encoding for the data of the encoding target column is completed, the backup performing unit deletes the backup column from the changed original table and activates the constraint conditions.

Device and method for encoding data column

Provided are a composition of a diagnostic biomarker for stomach cancer and a method of diagnosing stomach cancer using the same. The composition of a diagnostic biomarker for stomach cancer and the method of diagnosing stomach cancer using the same may be useful to determine stomach cancer from a patient with suspected stomach cancer.

Composition of diagnostic biomarker for stomach cancer and method of diagnosing stomach cancer using the composition

The present invention relates to a method for searching myelin using gonadotropin-releasing hormone receptors (GnRH-R) as a biomarker, more precisely, a method for investigating the distribution of myelin by immunohistochemical staining using GnRH-R antibody, based on the fact that GnRH-R and myelin are observed in the same region. The method for searching myelin of the invention can contribute to the studies on demyelination related degenerative brain disease and the disclosure of functions of myelin and the relation of myelin and GnRH-R.

Method for searching myelin using gonadotropin-releasing hormone receptors as a new biomarker

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Seoul, South Korea

Oh-Seung Kwon