Inspiremd, Ltd.

Microsoft Technology Licensing, LLC

Cell Buddy Network Ltd.

Ofir Paz

Eli Bar

Asher Holzer

Avishai Keren

Maier Fenster

Meir Feder

Zeev Asher Holzer

Erez Doron

Yoav Netzer

Yossi Dagan

Ilana Cohen

Simcha Aronson

Bar Eli

An intravascular device configured to treat an aneurysm that includes a support structure including metal struts configured to be positioned in a body lumen and defining a central fluid passage that extends axially along the support structure, and a knitted mesh cover disposed over an exterior thereof and across a radial arc and along a length of the support structure sufficient to exceed an opening of an aneurysm to be treated, and the cover includes a polymer fiber having a diameter of at least 40 nanometers to 30 microns and apertures therethrough, the apertures being sized to prevent blood from passing through the device to prevent further expansion of the aneurysm. Devices including apertures that are at least 20 microns and sized to minimize or prevent an aneurysm-filling material from exiting the aneurysm through the knitted mesh cover and support structure, and methods of stenting, are also encompassed.

Intravascular aneurysm treatment device and methods

Various stent assemblies for placement in a body lumen that includes a support element comprising metal struts constructed to be positioned in a body lumen, and a knitted layer or cover disposed over an interior, an exterior, or both, of the support element and along an entire length thereof, wherein the knitted layer or cover comprises a single polymer fiber or metal wire having a diameter of at least 40 nanometers to 30 microns, wherein the support element and knitted cover together have apertures sized 100 microns to 300 microns in diameter, or alternatively from 200 microns to 1500 microns, to block larger debris when the stent assembly is properly placed in a body lumen. Methods of stenting a body lumen by applying the stent assembly to a patient in need of treatment and expanding the stent assembly in situ are disclosed.

Stent assembly and methods for treatment via body lumens

Methods of providing a stent assembly that includes a stent jacket formed from an expansible mesh structure having apertures and that includes a fiber having a diameter of about 7 micrometers and about 40 micrometers, and an expansible stent operatively associated with the stent jacket. The method further comprises administering to the subject an active pharmaceutical ingredient (API) eluted from the stent assembly.

Methods of providing optimized drug-eluting stent assemblies

Optimized stent jacket having single fiber mesh

Disclosed is an assembly for opening a vessel lumen comprising a radially expandable stent configured to open a vessel lumen, the radially expandable stent comprises a curved wall having a proximal portion, a distal portion and a lumen connecting the proximal portion and the distal portion. The assembly further comprises a knitted jacket comprising a plurality of interconnected loops, the knitted jacket further comprising a tubular wall that substantially surrounds an exterior surface of the radially expandable stent, and at least one retainer belt that slidingly passes through at least one knitted loop of the plurality of interconnected loops in the knitted jacket.

Knitted stent jackets

A method of stenting, comprises: implanting a stent assembly in a vessel of a subject, the stent assembly, including: a stent jacket, comprising an expansible mesh structure, formed of fibers of a diameter between about 7 micrometers and about 18 micrometers, the diameter having a property of forming a substantially stable layer of endothelial cells, covering the fibers, thus reducing platelet aggregation, and an expansible stent, operatively associated with the stent jacket. The method further comprises administering to the subject an active pharmaceutical ingredient (API) comprising a platelet aggregation reducer for a shortened time period, not exceeding six months, the shortened time period being a consequence of the property. In accordance with some embodiments, the administration of a platelet aggregation.

Optimized stent jacket

An enhanced stent apparatus, comprising: a support element, wherein the support element is constructed to be positioned in a body lumen; and, a porous structure, the porous structure located on a surface of the support element, and wherein the porous structure is comprised of at least one fiber under 30 microns in diameter, has a coverage area of less than 30% and is provided with apertures.

Stent apparatuses for treatment via body lumens and methods of use

A stent assembly adapted to carotid arterial placement that includes a self-expanding support element comprising metal struts constructed to be positioned in a body lumen and expanded from a retracted state to an expanded state, and a knitted cover disposed over an exterior of the support element and along an entire length thereof, wherein the knitted cover comprises a single polymer fiber having a diameter of at least 40 nanometers to 30 microns, wherein the self-expanding support element and knitted cover together have apertures sized 20 microns to smaller than 100 microns in diameter to block larger debris when the stent assembly is placed in a carotid artery and expanded to the expanded state. Methods of stenting a carotid artery by applying the stent assembly to the carotid artery of a patient in need of treatment and expanding the stent assembly in situ are disclosed.

Carotid stent apparatus and methods for treatment via body lumens

A method of affixing a stent jacket to a stent, comprising aligning the stent jacket coaxially with the stent, placing a portion of the stent within a portion of the stent jacket, wherein a central axis of the stent is aligned with a central axis of the stent jacket, and affixing the stent jacket to the stent with a plurality of stitches, wherein the plurality of stitches form a plurality of consecutive loops that pass through one or more holes in the stent jacket and through an outer surface of the stent.

Stent-mesh assembly and methods

Methods of preparing and using a stent assembly that includes a stent jacket formed from an expansible mesh structure having apertures and that includes a fiber having a diameter of about 7 micrometers and about 40 micrometers, and an expansible stent operatively associated with the stent jacket. The method further comprises administering to the subject an active pharmaceutical ingredient (API) eluted from the stent assembly.

Optimized drug-eluting stent assembly methods

A method for establishing for a first smartphone a phone connection with a second smartphone, each smartphone comprising a phone and running a software application ('app'), the method comprising: exchanging, by operating the app, at least one permission message between the first and second smartphones; transmitting a first identifier from the first smartphone and a second identifier from the second smartphone to a call connector, responsive to a successful exchanging of the at least one permission message; and connecting a first phone call and a second phone call to establish a phone connection between the first and second smartphones, if the first phone call matches the first identifier and the second phone call matches the second identifier.

Call coupling

A smart card for use with a mobile communication device adapted to communicate over a cell-phone network, the smart card comprising: at least one communication port for communicating with a transceiver via a communication channel that is not a cell-phone channel; and a processor configured to receive from the transceiver an IMSI from a SIM having an authentication key, and an authentication response generated by the SIM responsive to the SIM's authentication key and a challenge by a cell-phone network, and to transmit the received IMSI and authentication response to the mobile communication device for transmission to the cell-phone network via a cell-phone communication channel provided by the cell-phone network.

Apparatus and method for interfacing with a cell-phone network

Disclosed is an assembly for filtering debris flowing in an in vivo fluid stream, the assembly comprising at least one balloon configured to volumetrically expand and, during at least a portion of the expansion, operatively connect with a filter, and to contract following the expansion. The assembly further comprising a filter configured to operatively connect with the at least one balloon during at least a portion of the volumetric expansion of the at least one balloon, such that the filter expands during the operative connection in order to filter debris from a fluid flowing in a fluid stream within which the expanded filter is disposed.

In vivo filter assembly

A stent assembly including a stent configured to be positioned in a body lumen, and a knitted stent jacket including an expansible mesh structure having a coverage area of less than 25%, having approximate aperture diameters greater than 20 micrometers, and surrounding an external surface of the stent and coaxially associated therewith, wherein the stent assembly elutes an amount of an active pharmaceutical agent.

Optimized drug-eluting stent assembly

A method of generating a compressed video stream, comprising: providing a plurality of display commands which represents a display; generating a plurality of quantized transform coefficients from said display commands, wherein said quantization is different for different display commands; and creating a compressed video stream utilization said coefficients.

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Rishon Lezion, Israel

Ofir Paz